Results 61 to 70 of about 2,259,386 (358)

Stromagenesis and cancer‐associated fibroblast heterogeneity in primary tumors and metastasis: focus in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
Cancer‐associated fibroblasts (CAFs) play different roles in NSCLC progression and metastasis. Their heterogeneous origins and phenotypes shape the tumor microenvironment and influence metastatic spread. This review highlights NSCLC CAF subtypes, their potential cellular sources, and their differential distribution across primary tumors and distant ...
Alejandro Bernardo, Natalia Díaz‐Valdivia, Patricia Fernández‐Nogueira, Jordi Alcaraz   +3 more
wiley   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

The Internet of Things for Health Care: A Comprehensive Survey

IEEE Access, 2015
The Internet of Things (IoT) makes smart objects the ultimate building blocks in the development of cyber-physical smart pervasive frameworks. The IoT has a variety of application domains, including health care.
S. M. Riazul Islam, Daehan Kwak, Md. Humaun Kabir, M. Hossain, K. Kwak   +4 more
semanticscholar   +1 more source

Exam‐level analysis of lecture capture viewing and student exam performance

FEBS Open Bio, EarlyView.
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley   +1 more source

Analysing inter-state communication dynamics and roles in the networks of the International Institute of Intellectual Cooperation

Humanities & Social Sciences Communications
The International Institute of Intellectual Cooperation (IIIC) was an international organisation established post-World War I, aimed to foster intellectual relations for global peace.
Rubén Rodríguez-Casañ, Elisabet Carbó-Catalan, Albert Solé-Ribalta, Diana Roig-Sanz, Javier Borge-Holthoefer, Alessio Cardillo   +5 more
doaj   +1 more source

Estimating local commuting patterns from geolocated Twitter data

EPJ Data Science, 2017
The emergence of large stores of transactional data generated by increasing use of digital devices presents a huge opportunity for policymakers to improve their knowledge of the local environment and thus make more informed and better decisions.
Graham McNeill, Jonathan Bright, Scott A Hale   +2 more
doaj   +1 more source

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock, Jihyun Park, Dae‐Gyu Jang, Bangyao Zhao, Samuel J. Teener, Ian F. Webber‐Davis, Lili Zhao, Eva L. Feldman, Stephen A. Goutman   +8 more
wiley   +1 more source

Perceived value of video games, but not hours played, predicts mental well-being in casual adult Nintendo players

Royal Society Open Science
Studies on video games and well-being often rely on self-report measures or data from a single game. Here, we study how 703 casually engaged US adults’ time spent playing for over 140 000 h across 150 Nintendo Switch games relates to their life ...
Nick Ballou, Matti Vuorre, Thomas Hakman, Kristoffer Magnusson, Andrew K. Przybylski   +4 more
doaj   +1 more source

Remaining Burden of Spinal Muscular Atrophy Among Treated Patients: A Survey of Patients and Caregivers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons, Natalie Land, Melissa Culhane Maravic, Claire Cagle, Amal Jamaleddine, Hemal Shah, Thomas Brown, Christabella Cherubino, Mouhamed Gueye   +8 more
wiley   +1 more source

Taking advantage of motif matrix inference for rotated image indexing and retrieval

EURASIP Journal on Advances in Signal Processing, 2018
With the rapid development of information technology, the sizes of digital libraries become larger and larger. How to quickly and effectively search the desired images in huge digital libraries becomes the challenge needed to resolve with high priority ...
Yi Xu, Wei Song, Yu Yan, Huadong Zhu, Ting Cao   +4 more
doaj   +1 more source