ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source
Novel Internet Advertising Approach to Raise Public Awareness About Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]
Inoue K +13 more
europepmc +1 more source
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas +6 more
wiley +1 more source
Prevalence of Problematic Digital Media Use Among Young Adults: Protocol for a Systematic Review. [PDF]
Chanmany Pastor RM +5 more
europepmc +1 more source
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo +6 more
wiley +1 more source
Protocol to design and implement scalable wireless network system for high-throughput, automated behavioral and circuit neuroscience in mice. [PDF]
Kim CY +12 more
europepmc +1 more source
Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang +3 more
wiley +1 more source
Addressing gender disparities in the efficacy of psychological interventions for behavioral addictions: protocol for a systematic review and individual patient data meta-analysis of randomized controlled trials. [PDF]
Laskowski NM +7 more
europepmc +1 more source
Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Internet Gaming Disorder, Sleep Quality, and Gaming Time Among High School and University Students in Saudi Arabia. [PDF]
Elsokkary EM +6 more
europepmc +1 more source

