Results 111 to 120 of about 131,152 (303)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

Active Ageing Index, New Emphasis Within the Same Methodology. The Role of the Internet

open access: yesStudia Universitatis Vasile Goldis Arad, Seria Stiinte Economice, 2019
Our paper focuses on the role of the Internet in older people’s lives and suggests that the weighting given to Internet usage should be increased when calculating the Active Ageing Index (AAI).
Berde Éva, Kuncz Izabella
doaj   +1 more source

Investigating consumer adoption, usage and impact of broadband: UK households

open access: yes, 2005
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Despite a large investment, the majority of countries especially the UK demonstrate a slow adoption of broadband.
Dwivedi, Yogesh Kumar
core  

Differential Item Functioning on the Patient Health Questionnaire 8 by Disease Subtype, Language, Sex, and Age Among People With Systemic Sclerosis: A Scleroderma Patient‐Centered Intervention Network Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu   +110 more
wiley   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

open access: yesArthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier   +12 more
wiley   +1 more source

Exploring the Relationships among Internet Usage, Internet Attitudes and Loneliness of Turkish Adolescents

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2008
As the average amount of time spent on the Internet is rapidly increasing, the starting age of Internet users is steadily decreasing. Thus, parents, psychologists, educators, technology creators and lawmakers must become aware of the potential risks and ...
Yavuz Erdoğan
doaj  

Excessive Internet use: Implications for sexual behaviour

open access: yes, 2000
The Internet appears to have become an ever-increasing part in many areas of people’s day-to- day lives. One area that deserves further examination surrounds sexual behavior and excessive Internet usage.
Griffiths, M, Griffiths, MD
core  

Conceptualizing the (non) users of the internet [PDF]

open access: yes, 2013
Most studies about internet use examine how usage differs among users and why. Less attention has been paid to the varied degrees of non-use or low levels of use. Non-adopters of digital media are usually understood as not having access to digital media.
Catherine Middleton   +5 more
core  

Formal and Informal Social Care in People With Rheumatic and Musculoskeletal Diseases: A Cross‐Sectional Multicenter Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro   +6 more
wiley   +1 more source

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