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Interpeduncular Nucleus and Avoidance Conditioning in the Rat

Science, 1960
Rats trained to make a jumping response to the onset of a visual stimulus lost the habit after damage to the interpeduncular nucleus of the midbrain. It was noted, however, that the majority of the operated animals showed perfect retention of the "fear" response to the conditioned stimulus.
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The Interpeduncular Nucleus

1986
Publisher Summary The interpeduncular nucleus (IPN) is a phylogenetically conserved area of the brain. Anatomically, the IPN is unique in that it is primarily an unpaired structure, but receives a significant input from a paired structure, the habenula (Hb).
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Interpeducular nucleus afferents in the rat

Brain Research, 1980
Afferents to the interpeduncular nucleus (IPN) of the rat were studied with the horseradish peroxidase (HRP) retrograde transport method. HRP was deposited microelectrophoretically in the IPN of adult rats. Major projections to the IPN originate in the medial habenular nucleus, the region surrounding the dorsal tegmental nucleus (accessory dorsal ...
E R, Marchand, J N, Riley, R Y, Moore
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The ultrastructure of enkephalin‐immunoreactive neurons in the interpeduncular nucleus of the rat

Journal of Comparative Neurology, 1986
AbstractThe interpeduncular nucleus of the rat is a complex structure, displaying diverse immunocytochemical and ultrastructural features. This nucleus contains opiate receptors, enkephalin‐positive cell bodies and enkephalin‐positive fibers. The ultrastructure of rat interpeduncular enkephalinergic neurons has not been described, nor has the role that
T J, Mahalik, T E, Finger
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The interpeduncular nucleus (ITP)

Cell and Tissue Research, 1977
Special types of cells of the interpeduncular nucleus (ITP) in the fog, Rana esculenta, are described after three typed of fixation: osmium tetroxide, aldehydes and potassium permanganate. Large granules with a sub-unit structure occurring together with bundles of filaments and elongated mitochondria are illustrated in the processes of cells, the ...
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Development of the interpeduncular nucleus in the midbrain of rhesus monkey and human

Anatomy and Embryology, 1978
The development of the interpeduncular nucleus (IPN) in primates was studied in rhesus monkey with 3H-thymidine autoradiographic, Nissl and Golgi methods and in humans in histological preparations from embryos and fetuses of different ages. Autoradiographic analysis demonstrated that the neurons of the monkey IPN underwent their final cell division ...
N J, Lenn, N, Halfon, P, Rakic
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Actions of cholinergic drugs on cells in the interpeduncular nucleus

Experimental Neurology, 1984
The muscarinic versus nicotinic effects of acetylcholine (ACh) on the activity of cells in the interpeduncular nucleus (IPN) of guinea pig brain slices were investigated using electrophysiologic techniques. Nicotinic and muscarinic drugs acted postsynaptically to increase the firing rate of cells in the IPN.
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Interpeduncular nucleus organization in the rat: Cytoarchitecture and histochemical analysis

Brain Research Bulletin, 1984
The organization of the interpeduncular nucleus (IPN) in the adult rat was analyzed using cytoarchitectonic, histochemical and immunohistochemical methods. Four paired and four unpaired subnuclei can be distinguished in the IPN on the basis of neuronal size, morphology, staining characteristics and packing density.
L M, Hemmendinger, R Y, Moore
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Lesion-induced catecholaminergic sprouting in the interpeduncular nucleus

Neurochemical Research, 1984
This work examined the capacity of intact catecholaminergic axon terminals to sprout in the partially deafferented interpeduncular nucleus (IPN). The results show that norepinephrine and dopamine levels were markedly increased in the IPN 6 weeks after bilateral habenula (Hb) lesions.
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Afferent connections of the interpeduncular nucleus and the topographic organization of the habenulo‐interpeduncular pathway: An HRP study in the rat

Journal of Comparative Neurology, 1981
AbstractThe HRP tracing method was employed to investigate the organization and afferent connections of the interpeduncular nucleus (IPN) in the rat. To study the topographical features of the different projections, a method was devised for obtaining HRP placements of limited size in different areas of the IPN.The main afferent connection of the IPN is
A, Contestabile, B A, Flumerfelt
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