Results 51 to 60 of about 226,983 (292)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

APPLICATION OF B-SPLINE METHOD IN SURFACE FITTING PROBLEM [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Fitting a smooth surface on irregular data is a problem in many applications of data analysis. Spline polynomials in different orders have been used for interpolation and approximation in one or two-dimensional space in many researches. These polynomials
F. Esmaeili, A. Amiri-Simkooei, V. Nafisi, A. Alizadeh Naeini   +3 more
doaj   +1 more source

A new multiscale algorithm for solving the heat conduction equation

Alexandria Engineering Journal, 2023
In this paper, a multiscale algorithm has been initially proposed for a numerical solution to the heat conduction equation. Firstly, the differential form of the heat conduction equation is transformed into an integral form, and then the time variable is
Yingchao Zhang, Yuntao Jia, Yingzhen Lin
doaj   +1 more source

Multipatch Approximation of the de Rham Sequence and its Traces in Isogeometric Analysis

, 2019
We define a conforming B-spline discretisation of the de Rham complex on multipatch geometries. We introduce and analyse the properties of interpolation operators onto these spaces which commute w.r.t. the surface differential operators.
Buffa, Annalisa, Dölz, Jürgen, Kurz, Stefan, Schöps, Sebastian, Vázques, Rafael, Wolf, Felix   +5 more
core   +1 more source

Strong coupling impurity solver based on quantics tensor cross interpolation [PDF]

Physical review B
Numerical methods capable of handling nonequilibrium impurity models are essential for the study of transport problems and the solution of the nonequilibrium dynamical mean field theory (DMFT) equations.
A. Kim, Philipp Werner
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A Non-Equilibrium Interpolation Scheme for IB-LBM Optimized by Approximate Force

Axioms, 2023
A non-equilibrium scheme and an optimized approximate force are proposed for the immersed boundary–lattice Boltzmann method (IB-LBM) to solve the fluid–structure interaction (FSI) equations.
Bowen Liu, Weiping Shi
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Efficiency analysis of polynomial filtering algorithms in navigation data processing for a class of nonlinear discrete dynamical systems

IET Control Theory & Applications, 2021
A polynomial filtering algorithm is designed for estimating a Markov sequence based on linear measurements. The feature of the estimation problem is that the Markov sequence is described by a nonlinear shaping filter, which is a second‐order polynomial ...
O. A. Stepanov, V. A. Vasiliev, M. V. Basin, V. A. Tupysev, Y. A. Litvinenko   +4 more
doaj   +1 more source

A Gaussian effective theory for gluon saturation

, 2002
We construct a Gaussian approximation to the effective theory for the Colour Glass Condensate which describes correctly the gluon distribution both in the low density regime at high transverse momenta (above the saturation scale $Q_s$), and in the high ...
Altarelli, Armesto, Armesto, Balitsky, Balitsky, Balitsky, Bartels, Bartels, Blaizot, Blaizot, Blättel, Braun, Buchmuller, Buchmuller, Buchmuller, Camici, Ciafaloni, Ciafaloni, Dokshitzer, Dumitru, Dumitru, Edmond Iancu, Fadin, Ferreiro, Ferreiro, Freund, Froissart, Gelis, Gelis, Gelis, Gelis, Golec-Biernat, Golec-Biernat, Golec-Biernat, Gribov, Gribov, Iancu, Iancu, Iancu, Iancu, Iancu, Iancu, Jalilian-Marian, Jalilian-Marian, Jalilian-Marian, Jalilian-Marian, Kazunori Itakura, Kharzeev, Kharzeev, Kharzeev, Kogut, Kovchegov, Kovchegov, Kovchegov, Kovchegov, Kovchegov, Kovner, Kozlov, Krasnitz, Krasnitz, Krasnitz, Kuraev, Kuraev, Lam, Lam, Larry McLerran, Levin, Levin, Levin, Levin, Levin, Levin, Lipatov, Lublinsky, McLerran, McLerran, McLerran, Mueller, Mueller, Mueller, Mueller, Mueller, Mueller, Mueller, Mueller, Mueller, Mueller, Nikolaev, Nikolaev, Salam, Staśto, Triantafyllopoulos, Weigert   +92 more
core   +2 more sources