Results 71 to 80 of about 226,983 (292)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The spaces of exponential type vectors of complex degrees of positive operators

Karpatsʹkì Matematičnì Publìkacìï, 2010
New classes of interpolation spaces of exponential type vectors of complex degrees of positive operators are defined. Properties of the approximation spaces generated by the considered interpolation spaces are investigated.
Dmytryshyn M.I.
doaj  

Semi-Rings, Semi-Vector Spaces, and Fractal Interpolation

Fractal and Fractional
In this paper, we introduce fractal interpolation on complete semi-vector spaces. This approach is motivated by the requirements of the preservation of positivity or monotonicity of functions for some models in approximation and interpolation theory. The
Peter Massopust
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Numerical convergence of nonlinear nonlocal continuum models to local elastodynamics

, 2018
We quantify the numerical error and modeling error associated with replacing a nonlinear nonlocal bond-based peridynamic model with a local elasticity model or a linearized peridynamics model away from the fracture set. The nonlocal model treated here is
Jha, Prashant K., Lipton, Robert
core   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

Analysis of relaxation time dependences on influencing factors in conducting oxides based on SnO2:Sb

Известия высших учебных заведений. Поволжский регион: Физико-математические науки
Background. Transparent conducting oxides (TCOs) based on SnO₂:Sb are promising materials for transparent electrodes in optoelectronic devices. Understanding the mechanisms of charge carrier conductivity and relaxation in these materials is crucial for ...
T.O. Zinchenko, E.A. Pecherskaya, V.D. Krevchik, I.A. Rubtsov, D.V. Yakushov, V.S. Aleksandrov   +5 more
doaj   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source

Interpolation, box splines, and lattice points in zonotopes [PDF]

Discrete Mathematics & Theoretical Computer Science, 2013
Given a finite list of vectors $X \subseteq \mathbb{R}^d$, one can define the box spline $B_X$. Box splines are piecewise polynomial functions that are used in approximation theory. They are also interesting from a combinatorial point of view and many of
Matthias Lenz
doaj   +1 more source