Results 221 to 230 of about 2,794,459 (245)

Personalized Interpretation of CBC and the Role of CRP in Early Detection and Monitoring of Blood Infection or Sepsis: A Diagnostic Perspective. [PDF]

Health Sci Rep
Muhunzi D, Mrema E, Banda F, Mashauri HL.   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Methodological Reflections from Engaging Five Culturally and Linguistically Unique U.S. Muslim Populations. [PDF]

Healthcare (Basel)
Ali AM, Salihu EY, Abdelwahab S, Shiyanbola OO, Vivian E, Chewning B.   +5 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Letter to the editor regarding to "association of acute kidney injury stages with in-hospital and long-term mortality in older adults with hip fractures". [PDF]

Ann Med
Liu S.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The challenges of implementing hybrid baselines for the interpretation of longitudinal behavioral data from individuals. [PDF]

NPJ Digit Med
Just SA, Tedeschi E, Holsbø E, Mikalsen KØ, Bongo LA, Homan P, Elvevåg B.   +6 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Characterizing Individuals Fulfilling Clinical Criteria for Limbic-Predominant Age-Related TDP-43 Encephalopathy in a Tertiary Memory Clinic. [PDF]

Neurology
Groot C, Calandri IL, Bader I, Bocancea DI, de Bruin H, Carrigan M, Collij LE, Duits FH, Kamps S, de Koning LA, Lemstra AW, Mastenbroek SE, Rikken RM, van Tol BGJ, Vermeiren MR, Wesseling A, Xia Y, Teunissen CE, van de Giessen E, Barkhof F, Jonkman LE, de Boer C, Rozemuller AJ, Leeuwis AE, van der Vlies AE, Tijms BM, van der Flier WM, Pijnenburg YAL, Coomans EM, Ossenkoppele R.   +29 more
europepmc   +1 more source