Results 171 to 180 of about 1,818,152 (349)

Understanding and interpreting a PRRS diagnosis in the context of “disease stages”

, 2021
A. Henao-Diaza, J. Jib, L. Gimenez-Lirolaa, D. H. Bauma, Jeffrey J. Zimmerman   +4 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Large language models and conditional rules in clinical decision support systems. [PDF]

Health Inf Sci Syst
Sivasothy S, Bingham A, Logothetis I, Barnett S, Abdelrazek M, Luckhoff C, Mathew J, Vasa R, Mouzakis K.   +8 more
europepmc   +1 more source

A New Interpretable State‐of‐Health Assessment Model for Lithium‐Ion Batteries With Multidimensional Adaptability Optimization [PDF]

Zongjun Zhang, Yuanyuan Qu, Yuxi Liu, Mengqi Li, Hongyu Li, Wei He   +5 more
openalex   +1 more source

Peer Review #1 of "Interpretable deep learning for the prediction of ICU admission likelihood and mortality of COVID-19 patients (v0.1)"

, 2022
Nazir Corresp, Hyacinth Kwadwo, Ampadu Equal, Amril Nazir, Ampadu Kwadwo, H Abdi, L Williams, I Bogoch, A Watts, A Thomas-Bachli, C Huber, M Kraemer, K Khan, F Bozkurt, M Tercan, G Patmano, T Tanrverdi, H Demir, U Yurekli, N Chawla, K Bowyer, L Hall, W Kegelmeyer, S Dahan, G Segal, I Katz, T Hellou, M Tietel, G Bryk, H Amital, Y Shoenfeld, A Dagan, M Dinevari, M Somi, E Majd, M Farhangi, Z Nikniaz, F Fernandes, T De Oliveira, C Teixeira, A De Moraes Batista, G Dalla Costa, A Chiavegatto Filho, F Gerayeli, S Milne, C Cheung, X Li, C Yang, A Tam, L Choi, A Bae, D Sin, M Goic, M Bozanic-Leal, M Badal, L Basso, D Graziani, J Soriano, D Rio-Bermudez, D Morena, T Daz, M Castillo, M Alonso, J Ancochea, S Lumbreras, J Izquierdo, H He, Y Bai, E Garcia, S Li, A Hyvarinen, K Ikemura, E Bellin, Y Yagi, H Billett, M Saada, K Simone, L Stahl, J Szymanski, D Goldstein, M Gil, K Leung, J Wu, D Liu, G Leung, Q Li, X Guan, P Wu, X Wang, L Zhou, Y Tong, R Ren, K Leung, E Lau, J Wong, X Li, P Ge, J Zhu, H Li, J Graham   +99 more
openalex   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Research on cross-dataset cardiac signal domain generalization and feature interpretability. [PDF]

Sci Rep
Li R, Aierken Y, Xu Y, Liu J, Tang Y.
europepmc   +1 more source

Using design principles as a lens to interpret user needs: a case study using a new 3D tic-tac-toe game [PDF]

J. Joshua Thomas, S. Rajath, Bhavani V. Sankar, Muzammil Bagewadi, Vishal Singh   +4 more
openalex   +1 more source

Listening to a patient: An exploratory experimental investigation into the effects of vocalization and therapist gender on interpreting clinical material [PDF]

, 2017
Barry Dauphin, Stacey Halverson, Sarah Pouliot, Linda H. Slowik   +3 more
openalex   +1 more source