Results 101 to 110 of about 2,956,075 (276)
City and space: a hermeneutic perspective
PerseitasThis paper presents a philosophical reflection on the city and the space. It proposes a different interpretation of the city, shifting the traditional focus on the historical and time-related aspects to a consideration of the space as a central category
Yobany Serna Castro
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Molecular Systems Biology, 2010 The interpretation of morphogen gradients is a pivotal concept in developmental biology, and several mechanisms have been proposed to explain how gene regulatory networks (GRNs) achieve concentration‐dependent responses.
James Cotterell, James Sharpe
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Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Memory, Interpretation, Identity
Teksty Drugie, 2016 The article investigates complex relations between memory, interpretation and identity, with special emphasis on the role of memory as a building material and of interpretation as a constructor of human identity.
Wojciech Kalaga
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Interpretation of Space Through Metaphors
Advances in Social Sciences Research Journal, 2018 The present paper aims to analyze the metaphorical representation of space from a cognitive point of view in the English language. To achieve this purpose it mostly focuses on the investigation of space metaphors. It also presents certain ways in which metaphoric expressions represent space.
openaire +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
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Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Protokolle zur Bibel, 2017 Origen’s interpretation in his first and second homilies on Exodus constitutes Egypt as a completely negative space. Egypt is the devil’s realm, the Pharaoh being the devil/the evil himself.
Agnethe Siquans
doaj
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
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