Results 81 to 90 of about 601,707 (261)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Christian Love in the Community
Diaconia, 2014 Framing a discussion of social space and the possibility of theological reflection and action, the article utilizes Moltmann, Nussbaum and Joost to argue that there is a space for God within social spaces.
Gerhard Wegner
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Space Behind Abstraction: The Metamorphosis of Shape
Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUAPurpose: to demonstrate the relation among various architectural contents, whose synthesis is materialized in the design of the architectural space. Method: to develop, in the context of the curricular unity of Drawing, of the Architecture Program, the ...
Ana Paula Parreira Correia Rainha +1 more
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
City and space: a hermeneutic perspective
PerseitasThis paper presents a philosophical reflection on the city and the space. It proposes a different interpretation of the city, shifting the traditional focus on the historical and time-related aspects to a consideration of the space as a central category
Yobany Serna Castro
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Molecular Systems Biology, 2010 The interpretation of morphogen gradients is a pivotal concept in developmental biology, and several mechanisms have been proposed to explain how gene regulatory networks (GRNs) achieve concentration‐dependent responses.
James Cotterell, James Sharpe
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Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Memory, Interpretation, Identity
Teksty Drugie, 2016 The article investigates complex relations between memory, interpretation and identity, with special emphasis on the role of memory as a building material and of interpretation as a constructor of human identity.
Wojciech Kalaga
doaj
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source