Results 61 to 70 of about 136,231 (263)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Surrogacy relationships: a critical interpretative review
Upsala Journal of Medical Sciences, 2020 Based on a critical interpretative review of existing qualitative research investigating accounts of ‘lived experience’ of surrogates and intended parents from a relational perspective, this article proposes a typology of surrogacy arrangements.
Jenny Gunnarsson Payne +2 more
doaj +1 more source
An interpretative phenomenological analysis of identity in the therian community
, 2014 Therianthropy is the belief that one is part nonhuman animal. Opinions vary in the academic literature as to whether it is a mental illness or a spiritual belief.
Clegg, Helen +8 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Interpretative Models of Legal Language
СибСкриптThe interpretative process of legal language is an activity aimed at reconstructing the mental representation of meaning. According to juridical linguistics, correct understanding of legal language requires more than mere linguistic skills: it needs ...
Olga V. Kobzeva
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Social inequalities and access to health: challenges for society and the nursing field
Revista Latino-Americana de Enfermagem, 2016 Objective to present a critical reflection upon the current and different interpretative models of the Social Determinants of Health and inequalities hindering access and the right to health.
Regina Celia Fiorati +2 more
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Positive aspects of the experience of psychosis: An interpretative phenomenological analysis [PDF]
, 2008 This qualitative study is an investigation of subjective accounts of Psychosis, with a particular focus on positive aspects of the experience from people who have continuing treatment needs and from those in recovery. The findings offer insight which is
Richards, Sarah Louise
core
A critical overview of interpretative phenomenological analysis: a contemporary qualitative research approach [PDF]
, 2017 Context: Interpretative Phenomenological Analysis (IPA) has become a dominant qualitative research methodology in many academic disciplines. The desire to understand the theoretical underpinnings of this research approach is evident.
Tuffour, Isaac, Isaac Tuffour
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source