Results 61 to 70 of about 354,301 (295)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The personal characteristics of witnesses as the basis of choice of tactics of interrogation

open access: yesПсихология и право, 2017
The article is devoted to studying of psychological features of persons influencing the choice of tactics of interrogation of witnesses. In this study 70 students took part with incomplete higher education between the ages of 18 to 21 years.
Zharinov A.I., Kalashnikova A.S.
doaj  

Electronic Recording of Police Interrogations [PDF]

open access: yes, 2019
Policy recommendation: All Virginia state law enforcement agencies to adopt a written department policy requiring electronic recording of any custodial interrogation conducted in a place of ...
Cleary, Hayley
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Human Being and the Philosophical Discourse

open access: yesEIRP Proceedings, 2012
The hypothesis from which we start our approach is the one according to which the philosophicaldiscourse is a specific way of communicating the reality. The base of the philosophical communication issurprise, doubt, uncertainty, anxiety, all generated by
Mirela Arsith
doaj  

Tactic of Involving a Specialist in Interrogation

open access: yesАрхів кримінології та судових наук
The research paper considers the methods of interacting with specialists and analyzes a situation when involvement of specialists in interrogation is required or recommended.
Olena Makarova
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Interrogation procedure for double addressed fiber Bragg structures as sensors of radiophotonic fewsensor system

open access: yesФизика волновых процессов и радиотехнические системы, 2018
Microwave photonic sensor systems represent a wide class of information systems with measurement conversion that use standardized analog and parallel links of parallel and sequential type with filtering, allowing to functionally displaying the ...
A.Zh. Sakhabutdinov, O.G. Morozov
doaj  

Safety and efficiency of emergency department interrogation of cardiac devices [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2016
Objective Patients with implanted cardiac devices may wait extended periods for interrogation in emergency departments (EDs). Our purpose was to determine if device interrogation could be done safely and faster by ED staff. Methods Prospective randomized,
James F. Neuenschwander   +6 more
doaj   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

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