Results 51 to 60 of about 354,301 (295)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Psychologists ‘Not Jack Bauer’, says the American Psychological Association
Voices in Bioethics, 2015 Ask just about any undergraduate student in psychology and it is likely they can list a handful of research studies in which they have participated. Whether it is the promise of an extra 2% added to their final grade, the allure of monetary compensation (
Elie Laskin
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A Parody of Love: the Narrative Uses of Rape in Popular Romance
Journal of Popular Romance Studies, 2012 Discussions of rape in popular romance have most often centered on how these scenes affect or reflect the lives of romance readers. Detractors of the genre have used its presence to support the notion that romance is a patriarchal and repressive literary
Angela R. Toscano
doaj
Проблеми Законності, 2016 Стаття присвячена дослідженню актуальної для сучасної правозастосовної практики проблеми, пов’язаної з забезпеченням прав та законних інтересів осіб під час їхнього допиту в режимі відеоконференції на стадії досудового розслідування.
Денис Олександрович Шингарьов
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
The Noun Phrase: Diversity in Dutch DP Design (DiDDD)
Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2007 In this paper we discuss our project: Diversity in Dutch DP Design. This project investigates the variation found in the Dutch DP. Not only the variation concerning contemporary dialects is taken into account, also the variation between contemorary Dutch
Marjo van Koppen +3 more
doaj +1 more source
Sensors, 2020 This article presents the effect of fiber Bragg gratings side lobes on interrogation systems consisting of sensor and matched filters. The conducted research shows that high-value side lobe structures applied as sensors and/or filters are characterized ...
Krzysztof Skorupski +3 more
doaj +1 more source
Conditions for Nondistortion Interrogation of Quantum System
, 2002 Under some physical considerations, we present a universal formulation to study the possibility of localizing a quantum object in a given region without disturbing its unknown internal state.
G.-C Guo +6 more
core +1 more source