Results 121 to 130 of about 402,183 (295)

Impact of the COVID-19 pandemic on the services provided by the Peruvian health system: an analysis of people with chronic diseases

open access: yesScientific Reports
During the pandemic, many individuals with chronic or infectious diseases other than COVID-19 were unable to receive the care they needed due to the high demand for respiratory care.
David Villarreal-Zegarra   +4 more
doaj   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao   +13 more
wiley   +1 more source

Causal Impact of the Hospital Readmissions Reduction Program on Hospital Readmissions and Mortality

open access: yes, 2018
Estimating causal effects of the Hospital Readmissions Reduction Program (HRRP), part of the Affordable Care Act, has been very controversial. Associational studies have demonstrated decreases in hospital readmissions, consistent with the intent of the ...
Choirat, Christine   +5 more
core  

Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning

open access: yesAdvanced Science, EarlyView.
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao   +14 more
wiley   +1 more source

The impact of generic reference pricing interventions in the statin market [PDF]

open access: yes
The objective of this study was to evaluate the intended and unintended impact on pharmaceutical use and sales of three public financing reforms applied to the prescription of statins: a Spanish generic reference pricing (RP) system for lovastatin and ...
Jaume Puig
core  

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

Interruption overload: telephones in Ford Madox Ford’s "4692 Padd", "A Call" and "A Man Could Stand Up" [PDF]

open access: yes, 2013
Ford Madox Ford’s short story “‘4692 Padd’” (1908), his novella A Call (1910), and his novel A Man Could Stand Up— (1926) all exploit the narratological potential of the rhetorical tropes of interruption.
McLoughlin, Kate
core  

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

open access: yesAdvanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li   +10 more
wiley   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

open access: yesAdvanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl   +12 more
wiley   +1 more source

Change in fertility rate and its influencing factors in 28 countries before and after the COVID-19 pandemic: linear modeling and interrupted time-series analysis

open access: yes陆军军医大学学报
Objective To analyze the changes in fertility trends of seasonally and calendar adjusted fertility rate (SAFR) in different countries before and after the COVID-19 pandemic outbreak and investigate the influence factors.
CHEN Yi, CHEN Yi, CHEN Qing, LIU Han
doaj   +1 more source

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