Results 131 to 140 of about 74,457 (256)

A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases

Advanced Science, EarlyView.
A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Heng Zhang, Yichong Sun, Xiaoting Zhang, Chi‐Kwan Lee, Zheng Li, Yehui Li, Huarong Chen, Paul D. Mitcheson   +7 more
wiley   +1 more source

Hospitalization cost trends for patients with impacted teeth: a double-breakpoint interrupted time series analysis. [PDF]

Front Public Health
An N, Jiang L, Song Y, Xiang R, Zhang J, Wang Y, Li F.   +6 more
europepmc   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Effects of China's National Volume-Based Procurement policy on utilisation and affordability of statins in children: an interrupted time series analysis. [PDF]

BMJ Open
Wu Y, Bai W, Liu F, Fan X, Liu S, Liu L, Jiang B, Yang Z.   +7 more
europepmc   +1 more source

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

Advanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen, Ming Li, Xuesheng Wang, Jiajia Sun, Ziyuan Zhang, Yongfeng Gong, Benkang Shi, Nengwang Yu, Yunuo Mao, Shengtian Zhao, Xiulin Zhang, Liqiang Guo   +11 more
wiley   +1 more source

Association between nirsevimab coverage and pediatric emergency department visits for bronchiolitis in 12 European countries: An interrupted time-series analysis. [PDF]

PLoS Med
Lenglart L, Titomanlio L, Alberti I, Almeida L, Aupiais C, Akyüz Özkan E, Barrett M, Basmaci R, Birbilen A, Borensztajn D, Schönenberger CB, Bressan S, Buonsenso D, Campos T, Castanhinha S, Chiaretti A, Claret G, De Zan F, Durnin S, Fodor L, Gomez B, Greber-Platzer S, Guedj R, Huege A, Leonard F, Maconochie IK, Marlow R, Milani G, Molina Gutierrez MA, Musolino AM, Oostenbrink R, Pucuka Z, Rivière S, Roland D, Rinder MR, Supino MC, Teksam O, Trenchs V, Valtuille Z, Vanda B, Vrijlandt S, Ouldali N, Nijman RG, EPISODES Study Group.   +43 more
europepmc   +1 more source

Responsive Open Microfluidic Logic for Mechanical Computing

Advanced Science, EarlyView.
Coupling elasticity with capillarity transforms mechanical compression into binary fluidic states, enabling deterministic logic in open microfluidic circuits. This work demonstrates that computation can emerge from interactions between mechanic and fluidic domains, establishing a general strategy for embedding information processing directly within ...
Roi Almog, Bat‐El Pinchasik
wiley   +1 more source

Epidemiology of Craniomaxillofacial Trauma in Chile: A Systematic Review and 24-Year Nationwide Interrupted Time-Series Analysis. [PDF]

Craniomaxillofac Trauma Reconstr
Sáenz-Ravello G, Carrasco García P, Sáenz-Ravello L, Fisher EL.   +3 more
europepmc   +1 more source

Interrupted Time-series Analysis

Japanese Journal of Drug Informatics, 2015
openaire   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source