Results 161 to 170 of about 764,488 (346)

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

The reporting quality of meta-epidemiological studies needs substantial improvement: a research on research study

Systematic Reviews
Background Meta-epidemiological research plays a vital role in providing empirical evidence needed to develop methodological manuals and tools, but the reporting quality has not been comprehensively assessed, and the influence of reporting guidelines ...
Youlin Long, Yurong Zheng, Xinyao Wang, Qiong Guo, Na Zhang, Ya Deng, Ruixian Tang, Zhengchi Li, Liang Du   +8 more
doaj   +1 more source

BZW1 Drives Immune Evasion in Lung Adenocarcinoma via Ferroptosis Suppression

Advanced Science, EarlyView.
BZW1 attenuates ferroptosis by competitively binding NCOA4 and suppress ferrtinophagy‐mediated iron release. The depletion of BZW1 triggers lipid peroxidation through iron homeostasis. Extracellularly, BZW1 attenuates immunogenic cell death and reinvigorates cytotoxic T‐cell responses.
Linyao Zhao, Yue Peng, Qing Liang, Shi Liu, Yang Li, Lei Ma, Menghan Hu, Sujuan Zheng, Zhihua Liu, Shugeng Gao   +9 more
wiley   +1 more source

The Influence of COVID-19 on Antimicrobial Resistance Trends at a Secondary Care Hospital in Slovenia: An Interrupted Time Series Analysis

Antibiotics
Background/Objectives. Our study aimed to determine the development of antibiotic resistance during the peri-pandemic period in a regional secondary care hospital using an interrupted time series analysis. Methods.
Samo Jeverica, Darja Barlič Maganja, Jani Dernič, Peter Golob, Alenka Stepišnik, Bojan Novak, Lea Papst, Anamarija Juriševič Dodič, Mladen Gasparini   +8 more
doaj   +1 more source

Scalable Manufacturing of Roll‐to‐Roll Slot‐Die Coated Perovskite Solar Cells

Advanced Science, EarlyView.
Roll‐to‐roll (R2R) slot‐die coating is emerging as a scalable pathway for perovskite solar cells. This mini‐review summarizes advances in ink design, drying control, and electrode integration that enable high‐efficiency flexible devices and modules. Challenges in throughput, stability, and sustainable processing are outlined, guiding the translation of
Farshad Jafarzadeh, MirKazem Omrani, Nathan S. Hill, Jazib Ali, Dumitru Sirbu, David G. Lidzey   +5 more
wiley   +1 more source

Spatial Heterogeneity in Spillover Effects of Assisted and Unassisted Rental Housing [PDF]

Three new contributions are added to the literature on subsidized rental housing impacts on nearby property values: 1) A primary focus on the spatial heterogeneity of these effects which warrants caution regarding citywide results; 2) an analysis by ...
Julia Koschinsky
core  

Impact of the COVID-19 pandemic on the services provided by the Peruvian health system: an analysis of people with chronic diseases

Scientific Reports
During the pandemic, many individuals with chronic or infectious diseases other than COVID-19 were unable to receive the care they needed due to the high demand for respiratory care.
David Villarreal-Zegarra, Luciana Bellido-Boza, Alfonso Erazo, Max Pariona-Cárdenas, Paul Valdivia-Miranda   +4 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Interruption overload: telephones in Ford Madox Ford’s "4692 Padd", "A Call" and "A Man Could Stand Up" [PDF]

, 2013
Ford Madox Ford’s short story “‘4692 Padd’” (1908), his novella A Call (1910), and his novel A Man Could Stand Up— (1926) all exploit the narratological potential of the rhetorical tropes of interruption.
McLoughlin, Kate
core