Results 61 to 70 of about 71,802 (256)

Trends in dengue incidence and lethality: interrupted time series analysis, Brazil, 2001-2022

Epidemiologia e Serviços de Saúde
Objective To analyze the temporal trend of dengue incidence and lethality rates and the proportions of its serotypes, in the different macro-regions of Brazil, between 2001 and 2022.
Tatiane Fernandes Portal de Lima Alves da Silva, Henry Maia Peixoto, Lúcia Rolim Santana de Freitas, Emerson Luiz Lima Araújo, Walter Massa Ramalho   +4 more
doaj   +2 more sources

Nano‐Scale Characterization of Impurities Segregation in Solid Oxide Electrolysis Cells

Advanced Functional Materials, EarlyView.
Cathodic polarization induces impurity segregation in Ni, forming an amorphous Na─Al─Si─O amorphous phase at grain boundaries. Under ultralow oxygen partial pressure, multiple elements dissolve, migrate, and reoxidize within the metal. A patterned model system provides direct nanoscale evidence, clarifying the mechanism of polarization‐driven impurity ...
Zhongtao Ma, Qingjie Wang, Bowen Li, Vasileios Bilalis, Søren Bredmose Simonsen, Ming Chen   +5 more
wiley   +1 more source

Three‐Dimensional Biomimetic Aerogel Conduits with Electro‐Ionic‐Immune Coupling Reverse the Pathological Cascade of Spinal Cord Injury

Advanced Functional Materials, EarlyView.
A biomimetic aerogel conduit was engineered from a nanofiber of gelatin/poly(l‐lactic acid) doped with polypyrrole nanoparticles, integrated with tannic acid and Mg2+. This “electro‐ionic‐immune” strategy mimicked spinal cord properties, reduced calcium overload, inflammation, oxidative damage, promoted neural stem cell differentiation, suppressed ...
Qingxiang Liu, Xin Yu, Jingtong Li, Chunyang Zheng, Yukang Zhang, Mingyu Jia, Tan Tian, Weiwei Zheng, Pinghui Zhou, Yingji Mao   +9 more
wiley   +1 more source

The impact of opioid prescribing guidelines on opioid dispensation: A systematic review and meta-analysis

Canadian Journal of Pain
Background Opioid prescribing guidelines for chronic noncancer pain (CNCP) aim to reduce opioid volume and dosage while addressing risks such as misuse, poisoning, and death.
Jihoon Lim, Parker Tope, Maximilian Schaefer, Isaiah Williams, Imen Farhat, Andrea Benedetti, Dimitra Panagiotoglou   +6 more
doaj   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Reduction of maternal mortality due to preeclampsia in Colombia-an interrupted time-series analysis

Colombia Medica, 2014
Introduction.  Preeclampsia is the most important cause of maternal mortality in developing countries. A comprehensive prenatal care program including bio-psychosocial components was developed and introduced at a national level in Colombia. We report on the trends in maternal mortality rates and their related causes before and after implementation of ...
Herrera, Julián A, Herrera-Medina, Rodolfo, Herrera-Escobar, Juan Pablo, Nieto-Díaz, Aníbal   +3 more
openaire   +4 more sources

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

Advanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe   +8 more
wiley   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

The impact of the national vaccination program on COVID-19 Infection Trends in Iran: An interrupted time series analysis [PDF]

فصلنامه ابن سینا
Background and aims: Various methods have been employed globally to prevent the spread of COVID-19. However, the effectiveness of vaccination in reducing COVID-19 infections requires further investigation.
Kolsoom Alimohamadi, Yousef Alimohamadi, Mojtaba Sepandi   +2 more
doaj  

The effect of mumps vaccine on the incidence of mumps in Hefei: An interrupted time-series analysis

Human Vaccines & Immunotherapeutics
To quantitatively assess the incremental protective effect of two-dose mumps vaccination in Hefei. Monthly mumps incidence during 2011–2023 were collected. The Interrupted Time Series and Segmented Regression Analyses (ITSA) were employed to evaluate the
Tingting Shi, Guangbo Qu, Yun Zhang, Lijuan Hou, Yuhui Jin   +4 more
doaj   +1 more source