Results 81 to 90 of about 764,488 (346)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

The Vulgar Conception of Objects in “Of Skepticism with Regard to the Senses” [PDF]

, 2007
In this paper, we see that contrary to most readings of T 1.4.2 in the Treatise, Hume does not think that objects are sense impressions. This means that Hume’s position on objects is not to be conflated with the vulgar perspective.
Rocknak, Stefanie
core   +1 more source

Effect of the COVID‐19 pandemic on the frequency of emergency department visits in Portugal: An interrupted time series analysis until July 2021

Journal of the American College of Emergency Physicians Open, 2023
Objectives This study aims to evaluate the effect of the COVID‐19 pandemic on the frequency of emergency department (ED) visits in Portugal between March 2020 and July 2021.
Sílvia Lopes, Patrícia Soares, Joana Santos Sousa, João Victor Rocha, Paulo Boto, Rui Santana   +5 more
doaj   +1 more source

Determinants of lung function development from birth to age 5 years: an interrupted time series analysis of a South African birth cohort

The Lancet Child & Adolescent Health
Summary Background Early life is a key period that determines long-term health. Lung development in childhood predicts lung function attained in adulthood and morbidity and mortality across the life course.
Carlyle Mccready, H. J. Zar, S. Chaya, C. Jacobs, L. Workman, Zoltán Hantos, Graham L. Hall, Peter D Sly, M. Nicol, D. Stein, Anhar Ullah, Adnan Custovic, F. Little, Diane M Gray   +13 more
semanticscholar   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Effectiveness and cost-effectiveness of implementing HIV testing in primary care in East London: protocol for an interrupted time series analysis [PDF]

, 2017
Introduction HIV remains underdiagnosed. Guidelines recommend routine HIV testing in primary care, but evidence on implementing testing is lacking. In a previous study, the Rapid HIV Assessment 2 (RHIVA2) cluster randomised controlled trial, we showed ...
Anderson, J, Apea, V, Barbosa, EC, Beresford, L, Boomla, K, Brown, A, Creighton, S, Delpech, V, El-Shogri, F, Estcourt, C, Figueroa, J, Fulop, N, Gilliham, S, Griffiths, C, Hutchinson, J, Leber, W, McMullen, H, Morris, S, Nightingale, C, Shahmanesh, M, Symonds, M   +20 more
core   +4 more sources

Accuracy of magnetic resonance imaging to identify pseudocapsule invasion in renal tumors [PDF]

, 2020
Purpose: To evaluate accuracy of MRI in detecting renal tumor pseudocapsule (PC) invasion and to propose a classification based on imaging of PC status in patients with renal cell carcinoma.
Altobelli, Emanuela, Angeletti, Silvia, Bellangino, Mariangela, Catalano, Carlo, Ciccozzi, Massimo, Del Monte, Maurizio, D’ovidio, Giulia, Faiella Eliodoro, Gallucci, Michele, Grasso, Francesco Rosario, Mastroianni, Riccardo, Muto, Giovanni, Panebianco, Valeria, Papalia, Rocco, Scarpa, Roberto Mario, Simone, Giuseppe   +15 more
core   +1 more source

Prescriptions of antidepressants and anxiolytics in France 2012–2022 and changes with the COVID-19 pandemic: interrupted time series analysis

BMJ Mental Health
Background Depression and anxiety have increased in prevalence since the start of the COVID-19 pandemic. Objective To evaluate the consumption of antidepressants and anxiolytics from 2012 to 2022 and the pandemic’s potential impact in France.
David De Bandt, Sarah R. Haile, Louise Devillers, Bastien Bourrion, D. Menges   +4 more
semanticscholar   +1 more source

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source

Epidemiology, prehospital care and outcomes of patients arriving by ambulance with dyspnoea: An observational study [PDF]

, 2016
Background: This study aimed to determine epidemiology and outcome for patients presenting to emergency departments (ED) with shortness of breath who were transported by ambulance.
Archer, Peter, Asha, Stephen Edward, Bryant, Michael, Chalkley, Dane, Chan, Barry, Cheri, Thomas, Chor, Melvin S Y, Cowell, David Lord, Craig, Simon, De Villecourt, Tracey, Duffy, Martin, Eley, Rob, Furyk, Jeremy, Goh, Shaun E., Graham, Colin A., Grummisch, Michelle, Haythorne, Helen, Holdgate, Anna, Jain, Nitin, Jones, Peter, Keijzers, Gerben, Kelly, Anne Maree, Kinnear, Frances, Klim, Sharon, Knott, Jonathan, Kuan, Win Sen, Laribi, Said, Lawoko, Charles, Lee, Francis Chun Yue, Lee, Kendall, Lee, Wee Yee, Leung, Ling Pong, Lozzi, Lydia, MacDonald, Stephen, Mahlangu, Mlungisi, Man, Chan Ka, Martin, Shane, McNulty, Richard, Meek, Robert, Morel, Douglas Gordon, Nguyen, Mai, Orda, Ulrich, Rahman, Nik Hisamuddin, Ritchie, Peter, Rosengarten, Pamela, Rosengren, David, Russell, Kerrie, Ryan, Alison, Saiboon, Ismail Mohd, Scott, Michael, Smith, Richard D B, Thom, Ogilvie, Thone, Jae, Watkins, Gina, Watson, Michael, Wilson, Kathryn, Wong, Chi Pang, Wong, Tai Wai   +57 more
core   +2 more sources