Results 131 to 140 of about 726,838 (342)

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Physician Incentives and Sex/Gender Differences in Depression Care: An Interrupted Time Series Analysis

Health Equity, 2020
Introduction: Physician incentives have been shown to reduce socioeconomic disparities in health care. The impact on sex/gender inequalities, however, has rarely been investigated.
doaj   +1 more source

Non‐Functionalized Graphene as an Electrical Sensing Surface for Bacterial Detection

Advanced Materials Interfaces, EarlyView.
Pathogenic bacteria detection in food remains a major public health concern, driving the need for rapid, cost‐effective, and portable detection systems. This review focuses on the use of non‐functionalized graphene as an electrical sensing surface for bacterial detection, highlighting their unique properties, sensing mechanism, and current developments.
Jazmin Berthe, Sara Giancaterino, Luciana Castillo, Cristiana Boi, Silvia Barbosa   +4 more
wiley   +1 more source

An Evaluation of the Impact of an OPEN Stewardship Generated Feedback Intervention on Antibiotic Prescribing among Primary Care Veterinarians in Canada and Israel

Animals
An interrupted time-series study design was implemented to evaluate the impact of antibiotic stewardship interventions on antibiotic prescribing among veterinarians.
Kamal R. Acharya, Adar Cohen, Gabrielle Brankston, Jean-Paul R. Soucy, Anette Hulth, Sonja Löfmark, John S. Brownstein, Nadav Davidovich, Moriah E. Ellen, David N. Fisman, Jacob Moran-Gilad, Amir Steinman, Derek R. MacFadden, Amy L. Greer   +13 more
doaj   +1 more source

High Stability of Diketopyrrolopyrrole Polymer Transistors Under Aqueous Condition Toward Biosensing Platform

Advanced Materials Technologies, EarlyView.
We are reporting the first‐time investigation of DPP‐based Organic Field‐Effect Transistor (OFET) devices with high‐stability of signal response in both of ambient and aqueous conditions with PBS solution. ABSTRACT Diketopyrrolopyrrole (DPP)–based conjugated polymers show strong promise for electronic applications, including bioelectronic gas sensors ...
Chattarika Khamhanglit, Yudai Hemmi, Ami Ichikawa, YuanTong Gu, Kuniaki Nagamine, Hiroyuki Matsui, Prashant Sonar   +6 more
wiley   +1 more source

A High Throughput Microfluidic Approach for the Continuous Manufacture of Ibuprofen Nanocrystals

Advanced Materials Technologies, EarlyView.
A robust, continuous manufacturing platform using a high‐throughput microfluidic reactor addresses key scalability challenges in pharmaceutical production. This process efficiently generates crystalline ibuprofen nanoparticles with superior control over size and distribution.
Shorooq Abukhamees, Maximilian Besenhard, Rawan Fitaihi, Hei Ming Kenneth Ho, Asterios Gavriilidis, Duncan Q. M. Craig   +5 more
wiley   +1 more source

Effect of flood on the cutaneous leishmaniasis incidence in northeast of Iran: an interrupted time series study

BMC Infectious Diseases
Introduction Cutaneous Leishmaniasis (CL) is a zoonosis infection which is endemic in more than 100 countries in Asia, Africa, Europe and America. It was estimated that nearly 20 thousand of new cases are reported in Iran annually.
Mostafa Majidnia, Atefeh Khoshkchali, Ahmad Khosravi   +2 more
doaj   +1 more source

Association Between Introduction of the 23-valent Pneumococcal Polysaccharide Vaccine (PPSV23) and Pneumonia Incidence and Mortality Among General Older Population in Japan: A Community-based Study

Journal of Epidemiology
Background: With global aging, especially in Asia, preventing pneumonia among seniors is vital. The necessity of introducing pneumococcal vaccines among the elderly has been highlighted, but there is a paucity of community-based real-world evidence on ...
Aya Sugiyama, Masaaki Kataoka, Kentaro Tokumo, Kanon Abe, Hirohito Imada, Bunlorn Sun, Golda Ataa Akuffo, Tomoyuki Akita, Shingo Fukuma, Noboru Hattori, Junko Tanaka   +10 more
doaj   +1 more source

The impact of the COVID-19 lockdown on HIV care in 65 South African primary care clinics: an interrupted time series analysis

The Lancet HIV, 2021
J. Dorward, Thokozani Khubone, Kelly R. Gate, Hope Ngobese, Yukteshwar Sookrajh, Siyabonga Mkhize, A. Jeewa, C. Bottomley, Lara Lewis, K. Baisley, C. Butler, Nomakhosi Gxagxisa, N. Garrett   +12 more
semanticscholar   +1 more source

Advances in Safe, Flexible, and Stretchable Batteries for Wearable Applications

Advanced Materials Technologies, EarlyView.
Unlike previous reviews centered on component‐based deformability, this work highlights safety‐driven design strategies for flexible and stretchable batteries. By integrating material‐level engineering, geometry‐controlled structures, biocompatibility, and self‐protection mechanisms, it establishes a unified framework that connects mechanical ...
Hyewon Kang, Garan Byun, Seunghyeb Ban, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source