Results 31 to 40 of about 35,337,675 (295)

Trends in neurosurgical care in Western Uganda: an interrupted time series analysis [PDF]

Neurosurgical Focus, 2018
OBJECTIVE In addition to the rising burden of surgical disease globally, infrastructure and human resources for health remain a great challenge for low- and middle-income countries, especially in Uganda. In this study, the authors aim to explore the trends of neurosurgical care at a regional referral hospital in
Jihad, Abdelgadir, Cyrus, Elahi, Jacquelyn, Corley, Kevin C, Wall, Josephine N, Najjuma, Alex, Muhindo, Joao Ricardo, Nickenig Vissoci, Michael M, Haglund, David, Kitya   +8 more
openaire   +2 more sources

The impact of hospital accreditation on quality measures: an interrupted time series analysis [PDF]

BMC Health Services Research, 2015
Developing countries frequently use hospital accreditation to guarantee quality and patient safety. However, implementation of accreditation standards is demanding on organisations. Furthermore, the empirical literature on the benefits of accreditation is sparse and this is the first empirical interrupted time series analysis designed to examine the ...
Devkaran, Subashnie, O’Farrell, Patrick N   +1 more
openaire   +2 more sources

Non-crossing quantile double-autoregression for the analysis of streaming time series data [PDF]

, 2023
Data availability statement: The data that support the findings of this study are openly available in Yahoo Finance at https://hk.finance.yahoo.com.Many financial time series not only have varying structures at different quantile levels and exhibit the ...
Choy, SK, Yu, K, Jiang, R
core   +1 more source

Methodological considerations for interrupted time series analysis in radiation epidemiology: an overview

Journal of Radiological Protection, 2021
Abstract Interrupted time series analysis (ITSA) is a method that can be applied to evaluate health outcomes in populations exposed to ionizing radiation following major radiological events. Using aggregated time series data, ITSA evaluates whether the time trend of a health indicator shows a change associated with the radiological ...
Daniel Wollschläger, Anssi Auvinen, Maria Blettner, Hajo Zeeb   +3 more
openaire   +3 more sources

MultiCenter Interrupted Time Series Analysis: Incorporating Within and Between-Center Heterogeneity

Clinical Epidemiology, 2020
Joycelyne E Ewusie,1,2 Lehana Thabane,1 Joseph Beyene,1 Sharon E Straus,3 Jemila S Hamid1,2,4 1Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; 2School of Epidemiology and Public Health ...
Ewusie JE, Thabane L, Beyene J, Straus SE, Hamid JS   +4 more
doaj  

Excess mortality during the Coronavirus disease pandemic in Korea

BMC Public Health, 2023
Background Although the ongoing epidemics of Coronavirus disease 2019 (COVID-19) may have affected the mortality trend of the nation, the national level assessment of excess mortality (changes in overall mortality in the entire population) is still ...
Changwoo Han, Hoyeon Jang, Juhwan Oh
doaj   +1 more source

Impact of Covid-19 pandemic on tuberculosis mortality in Brazil: a time series analysis [PDF]

Revista de Saúde Pública
OBJECTIVE: To evaluate changes in the trend of tuberculosis mortality in Brazil over recent decades and assess the impact of the Covid-19 pandemic on this indicator.
Bernardo Bastos Wittlin, Felipe Bezerra Pimentel Araújo, Antônio Augusto Moura da Silva   +2 more
doaj   +2 more sources

Impact of the acute national blood culture bottle shortage on the two-set blood culture rate in a single center in Japan: Insights from an interrupted time-series analysis

Infection Prevention in Practice
Summary: Background: In 2024, a worldwide shortage of blood culture bottles prompted efforts to mitigate its impact, including strategies to reduce blood culture orders.
Tetsuji Morishita, Masao Kuwabara, Masayoshi Monji, Shin Lee, Makoto Hayashi, Hisashi Tsurumi, Hidetoshi Matsunami   +6 more
doaj   +1 more source

Hospitalization of mild cases of community-acquired pneumonia decreased more than severe cases during the COVID-19 pandemic

International Journal of Infectious Diseases, 2021
Objective: The coronavirus disease 2019 (COVID-19) pandemic has affected all healthcare systems. This study aimed to assess the impact of the COVID-19 pandemic on the number and severity of cases of community-acquired pneumonia (CAP) in Japan.
Hiroyuki Nagano, Daisuke Takada, Jung-ho Shin, Tetsuji Morishita, Susumu Kunisawa, Yuichi Imanaka   +5 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source