Results 51 to 60 of about 68,355 (266)

Sparks from the Tail of a Comet: Historical Materialism and Genetic Imperialism in Octavia E. Butler’s Xenogenesis Novels [PDF]

open access: yesIntersections, 2016
Through a close reading of Octavia Butler’s Dawn (1987), Adulthood Rites (1988) and Imago (1989), this article examines how implicitly decolonialist science fiction is shaped by the socio-historical context of the Cold War.
Sandra Cox
doaj  

“Nobody told me”: Chicana Women’s Madness and Mourning in Sandra Cisneros’s Have You Seen Marie?

open access: yesIntersections, 2021
“‘Nobody told me’: Chicana Women’s Madness and Mourning in Sandra Cisneros’s Have You Seen Marie?” employs interdisciplinary research to understand Sandra Cisneros’ tale of women’s mental illness in Have You Seen Marie?.
Lindsay M. Vreeland
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Remapping the Jazz Singer from the 1920s to the 1980s [PDF]

open access: yesIntersections, 2016
The Jazz Singer (1927), a film based on Samson Raphaelson’s short story, “The Day of Atonement,” published in 1922, and inspired by the life of one of the most successful twentieth century Jewish actors, Al Jolson, played an important role in the film ...
Maria-Nicoleta Tirica
doaj  

Silence and Resistance in Margaret Atwood’s Alias Grace

open access: yesIntersections, 2021
Silence is a concept both praised and criticised when put to practice. The latest trends in society encourage individuals to be their true selves; simultaneously, some are reproached for presenting too much of themselves to the world.
Sara Calvo de Mora Mármol
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Mobility and Identity in Ladee Hubbard’s The Talented Ribkins

open access: yesIntersections
This article examines themes of mobility and identity Ladee Hubbard’s The Talented Ribkins (2017). I use the lens of mobility studies to closely analyze the novel’s two primary characters, Johnny and Eloise, and the ways in which their cross-Florida road
Cameron Williams Crawford
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Editorial Foreword

open access: yesRevista Română pentru Studii Baltice şi Nordice, 2011
This issue of Revista Română pentru Studii Baltice şi Nordice [The Romanian Journal of Baltic and Nordic Studies, RRSBN] carries selected papers presented in approximately half of the panels of the second international conference for Baltic and Nordic ...
Silviu Miloiu
doaj  

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy