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Origin and Development of Interstitial Cells of Cajal

The International Journal of Developmental Biology
The digestive tract is a series of organs with specific functions and specialized anatomy. Each organ is organized similarly with concentric layers of epithelial, connective, smooth muscle, and neural tissues. Interstitial cells of Cajal (ICC) are distributed in smooth muscle layers and contribute to the organization of repetitive and rhythmic smooth ...
Tara, Sweet   +2 more
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Comparative Study of Interstitial Cells of Cajal

Cells Tissues Organs, 1987
The cells present in the alimentary canal, contacting both nerve endings and smooth muscle cells and named interstitial cells of Cajal, show different ultrastructural features. A comparative study has been performed in order to see if these differences can be related to the animal species studied or to the interstitial cell localizations inside the ...
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Interstitial Cells of Cajal in the Urinary Tract

2011
The study of novel interstitial cells in the tissues of the urinary tract has defined advances in the field in the last decade. These intriguing cells belong to the same family as the better known interstitial cells of Cajal (ICC) of the gastrointestinal tract, and their discovery has been interpreted to suggest that pacemaker cells may be present in ...
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Interstitial cells of Cajal in health and disease

Neurogastroenterology & Motility, 2008
Abstract  The gastrointestinal tract serves the physiological function of digesting and absorbing nutrients from food and physically mixing and propelling these contents in an oral to anal direction. These functions require the coordinated interaction of several cell types, including enteric nerves, immune cells and smooth muscle. Interstitial cells of
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Alterations in the Density of Interstitial Cells of Cajal in Achalasia

Digestive Diseases and Sciences, 2007
The aim of this study was to assess the quantity of interstitial cells of Cajal (ICC) in the lower esophageal sphincter (LES) in achalasia. LES muscle was obtained from 11 achalasia and nine esophageal cancer (control) patients during surgery. Immunohistochemistry was performed and average cell counts per high-power field (HPF) were obtained.
Arman, Kilic   +5 more
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Ontogeny of interstitial cells of cajal in the human intestine

Journal of Pediatric Surgery, 1999
Interstitial cells of Cajal (ICC) recently have been identified as intestinal pacemaker cells. Abnormalities in ICC are increasingly recognized in a number of neonatal disorders such as infantile hypertrophic pyloric stenosis, Hirschsprung's disease, and transient intestinal pseudo-obstruction.
S E, Kenny   +6 more
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Interstitial Cajal-like cells in human gallbladder

Journal of Molecular Histology, 2007
We describe here an interstitial Cajal-like cell type (ICLC) in human gallbladder, resembling the archetypal enteric interstitial cells of Cajal. Gallbladder ICLC were demonstrated in fresh preparations (tissue cryosections) using methylene-blue, and fixed specimens in Epon semi-thin sections stained with toluidine blue or transmission electron ...
Mihail E, Hinescu   +3 more
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Distribution of the interstitial cells of Cajal in the human anorectum

Journal of the Autonomic Nervous System, 1998
The interstitial cells of Cajal are proposed to have a role in the control of gut motility. The aim of this study was to establish the distribution of interstitial cells of Cajal in the wall of the normal human anorectum. Interstitial cells of Cajal express the proto-oncogene c-kit.
R, Hagger   +3 more
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[Cajal interstitial cells identification].

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 2003
Cajal interstitial cells are cells that are found in the abdominal digestive system wall, between neurons and smooth muscular tissue. They are considered to be pacemakers for slow intestinal waves. The paper discuss about the electron-microscopic identification of Cajal interstitial cells in the rat small intestine wall, cell morphology, placement of ...
F, Filipoiu   +5 more
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One hundred years of interstitial cells of Cajal

Microscopy Research and Technique, 1999
This review is a portrayal of the evolution of ideas involving the interstitial cells of Cajal in changing disguises as dull fibroblasts, not very exciting Schwann cells, or perhaps quite important, though primitive neurons. However, today unmasked (we believe), they reveal themselves as myoid cells, a role that, judging by current interest, is far ...
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