Results 21 to 30 of about 24,520 (298)

Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine.

open access: greenAmerican Journal of Physiology - Gastrointestinal and Liver Physiology, 2017
J. Malysz   +10 more
semanticscholar   +2 more sources

Hyperplasia of interstitial cells of cajal in sprouty homolog 4 deficient mice. [PDF]

open access: yesPLoS ONE, 2015
Gastrointestinal stromal tumors, which are thought to derive from interstitial cells of Cajal or their precursors, often harbor an oncogenic mutation of the KIT receptor tyrosine kinase.
An Thys   +5 more
doaj   +1 more source

Interstitial cells of Cajal and human colon motility in health and disease.

open access: yesAmerican Journal of Physiology - Gastrointestinal and Liver Physiology, 2021
Our understanding of human colonic motility, and autonomic reflexes that generate motor patterns, has increased markedly through high-resolution manometry.
J. Huizinga, Amer Hussain, Ji-Hong Chen
semanticscholar   +1 more source

Interstitial cells of Cajal, from structure to function [PDF]

open access: yesFrontiers in Neuroscience, 2013
1 Department of Medicine, Farncombe Family Intestinal Health Research Institute, McMaster University, Hamilton, ON, Canada 2 Department of Gastroenterology and Hepatology, Wuhan University Institute of Digestive and Liver diseases, Renmin Hospital of Wuhan University, Wuhan, China 3 Department of Cellular and Molecular Medicine, University of ...
Jan D Huizinga   +6 more
doaj   +4 more sources

Pathophysiological Implications of Interstitial Cajal-like Cells (ICC-like) in Uterus: A Comparative Study with Gastrointestinal ICCs

open access: yesCurrent Issues in Molecular Biology, 2023
The main function of interstitial cells of Cajal (ICCs) is to regulate gastrointestinal peristalsis by acting as a “pacemaker” cell by generating spontaneous slow electrical waves.
Laura López-Pingarrón   +3 more
doaj   +1 more source

Sporadic Congenital Hyperplasia of Interstitial Cell of Cajal of Rectum as a Cause of Chronic Constipation [PDF]

open access: yesIranian Journal of Colorectal Research, 2013
Gastrointestinal stromal tumors (GIST) are the usual primary mesenchymal neoplasms of the GI tract. Interstitial cells of Cajal (ICCs) are intestinal pacemaker cells that instigate peristalsis in the stomach and intestine, and are measured to be ...
Alimohammad Bananzadeh   +6 more
doaj   +1 more source

Colonic Motility is Improved by the Activation of 5-HT2B Receptors on Interstitial Cells of Cajal in Diabetic Mice.

open access: yesGastroenterology, 2021
BACKGROUND & AIMS Constipation is commonly associated with diabetes. Serotonin (5-HT), produced predominantly by enterochromaffin (EC) cells via tryptophan hydroxylase 1 (TPH1), is a key modulator of gastrointestinal (GI) motility.
Byungchang Jin   +9 more
semanticscholar   +1 more source

A New Paradigm Shift in Gastroparesis Management

open access: yesGut and Liver, 2022
Gastroparesis, once regarded as a rare disease, is difficult to diagnose and challenging to treat; there were many breakthrough advances in the 2010s, shifting the paradigm of the understanding of this complex entity and its management.
Parit Mekaroonkamol   +2 more
doaj   +1 more source

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