Results 61 to 70 of about 11,466 (188)

Pathophysiology of interstitial cystitis [PDF]

open access: yesInternational Journal of Urology, 2019
AbstractInterstitial cystitis/bladder pain syndrome is a chronic pain syndrome whose causes remains elusive with no generally accepted treatment. A hallmark of functional pain syndromes such as interstitial cystitis/bladder pain syndrome is pain in the absence of demonstrable pathology of the viscera or associated nerves.
openaire   +2 more sources

3D MR Fingerprinting for Quantitative Bladder Wall T1, T2, and M0 Mapping in Healthy Subjects at 1.5 T and 3 T

open access: yesNMR in Biomedicine, Volume 39, Issue 9, September 2026.
Current diagnostic tests for lower urinary tract symptoms lack the ability to assess tissue‐level alterations in the bladder wall. This study introduces an approach for simultaneous high‐resolution 3D T1, T2, and proton density mapping of the bladder wall using magnetic resonance fingerprinting combined with a self‐supervised deep learning ...
Shane A. Wells   +5 more
wiley   +1 more source

Interleukin-33 and Mast Cells Bridge Innate and Adaptive Immunity: From the Allergologist’s Perspective [PDF]

open access: yesInternational Neurourology Journal, 2015
Interleukin (IL) 33, a member of the IL-1 superfamily, is an “alarmin” protein and is secreted in its active form from damaged cells undergoing necrotic cell death. Mast cells are one of the main effector cell types in allergic disorders.
Tae Young Jang, Young Hyo Kim
doaj   +1 more source

Diagnostic Model Development for IC/BPS and Its Subtypes Using Clinical Indicators, Urinary Biomarkers, and Single‐Cell Transcriptomic Analysis

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Subjects were divided into HC, NHIC, and HIC groups. Clinical Characteristics, urinary ultrasound parameters, and urinary biomarkers were collected for ML screening of predictive signatures. DEGs are identified from GEO transcriptomic data; scRNA‐seq delineates cell clusters, pseudotime trajectories and intercellular communication.
Cheng Luo   +5 more
wiley   +1 more source

Causal effects of gut microbiota on risk of interstitial cystitis: a two-sample Mendelian randomization study

open access: yesFrontiers in Microbiology
BackgroundThe correlation between gut microbiota and interstitial cystitis has garnered significant attention in previous studies. Nevertheless, the causal relationship between them remains to be clarified.MethodsGenetic variation serves as a tool in ...
Jianguo Gao, Sihai Shao, Yuefan Shen
doaj   +1 more source

Successful treatment of eosinophilic cystitis with benralizumab

open access: yesUrology Case Reports, 2020
Eosinophilic cystitis is a rare form of interstitial cystitis. It can be chronic and debilitating due to urinary frequency, dysuria, incontinence, and frequent urinary tract infections.
W Donald Cooke, Abigail J Tarr Cooke
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, Volume 73, Issue 8, August 2026.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Hysteroscopy metroplasty for partial septate uterus: Just a matter of infertility?

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 174, Issue 2, Page 906-912, August 2026.
Abstract Objective The primary objective of this study is to assess the impact of hysteroscopic metroplasty on symptom relief, including dysmenorrhea, dyspareunia, and menstrual blood flow in women with partial uterine septa (U2a class). Additionally, the study aims to investigate potential correlations between clinical and ultrasonographic ...
Alessandro Arena   +9 more
wiley   +1 more source

Multiple congenital anomalies in a neonatal goat kid: Atresia ani, rectovaginal fistula, renal fusion, ectopic ureter and sinus of Valsalva aneurysm

open access: yesVeterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 2‐week‐old female Anglo‐Nubian goat kid was presented with rectal malformation and signs of lower urinary and gastrointestinal dysfunction. Postmortem examination revealed multiple congenital anomalies including atresia ani with a rectovaginal fistula, right‐sided extramural ectopic ureter, renal fusion with unilateral severe pallor and ...
Caro Wilson   +3 more
wiley   +1 more source

The efficacy and Safety of Intravesical Bacillus-Calmette-Guerin in the Treatment of Female Patients with Interstitial Cystitis: A double-blinded Prospective Placebo Controlled Study

open access: yesUrology Journal, 2004
Purpose: To evaluate the efficacy and safety of intravesical Bacillus Calmette-Gurein injection in the treatment of female patients with interstitial cystitis.
AA Khezri, M Heidari, Darioush Irani
doaj  

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