Results 71 to 80 of about 21,422 (233)
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Interleukin-33 and Mast Cells Bridge Innate and Adaptive Immunity: From the Allergologist’s Perspective [PDF]
International Neurourology Journal, 2015 Interleukin (IL) 33, a member of the IL-1 superfamily, is an “alarmin” protein and is secreted in its active form from damaged cells undergoing necrotic cell death. Mast cells are one of the main effector cell types in allergic disorders.
Tae Young Jang, Young Hyo Kim
doaj +1 more source
D-mannose: a promising support for acute urinary tract infections in women. A pilot study [PDF]
, 2016 Urinary tract infections still represent a significant bother for women and result in high costs to the health system. D-mannose is a simple sugar; it seems able to hinder bacteria adhesion to the urothelium.
BENEDETTI PANICI, PIERLUIGI +6 more
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Pathophysiology of interstitial cystitis [PDF]
International Journal of Urology, 2019 AbstractInterstitial cystitis/bladder pain syndrome is a chronic pain syndrome whose causes remains elusive with no generally accepted treatment. A hallmark of functional pain syndromes such as interstitial cystitis/bladder pain syndrome is pain in the absence of demonstrable pathology of the viscera or associated nerves.
openaire +2 more sources
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective To compare the 3‐month effectiveness of galcanezumab with select traditional oral migraine preventive (TOMP) medications recommended by scientific societies (TOMP efficacy subset) and with the most frequently used individual TOMP medications.
Shivang Joshi +7 more
wiley +1 more source
Successful treatment of eosinophilic cystitis with benralizumab
Urology Case Reports, 2020 Eosinophilic cystitis is a rare form of interstitial cystitis. It can be chronic and debilitating due to urinary frequency, dysuria, incontinence, and frequent urinary tract infections.
W Donald Cooke, Abigail J Tarr Cooke
doaj +1 more source
Effects of repeated exposure to ozonated water on hair fibre structure and integrity: Part I
International Journal of Cosmetic Science, EarlyView.Repeated exposure to ozonated water caused cumulative oxidative changes in hair, altering structural integrity, thermal behaviour and mechanical properties. The findings reveal a distinct ozone‐induced damage profile that progresses beyond the cuticle, challenging claims of hair‐revitalizing benefits. Abstract Objective Ozone has recently been marketed
Pedro Augusto Laurindo Igreja Marrafa +5 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan +3 more
wiley +1 more source
Frontiers in MicrobiologyBackgroundThe correlation between gut microbiota and interstitial cystitis has garnered significant attention in previous studies. Nevertheless, the causal relationship between them remains to be clarified.MethodsGenetic variation serves as a tool in ...
Jianguo Gao, Sihai Shao, Yuefan Shen
doaj +1 more source