Results 81 to 90 of about 21,422 (233)

Urinary tract infections in the community [PDF]

open access: yes, 2014
Urinary tract infections (UTIs) are defined as significant bacteriuria in the setting of symptoms of cystitis/pyelonephritis. Urine dipstick is diagnostic in most cases.
Bonnici, Jason J.
core  

Botulinum A toxin intravesical injections in the treatment of painful bladder syndrome: A pilot study [PDF]

open access: yes, 2006
Objective: We evaluated the efficacy and tolerability of botulinum A toxin (BTX-A) intravesical injections in patients affected by painful bladder syndrome with increased urinary frequency, refractory to conventional treatment modalities. Methods: Twelve
Bini, V   +5 more
core   +2 more sources

Real‐World Patient Characteristics and Treatment Patterns Among Patients With Interstitial Cystitis (IC)/Bladder Pain Syndrome (BPS)

open access: yesReproductive, Female and Child Health, Volume 5, Issue 2, June 2026.
ABSTRACT Objective Interstitial cystitis/bladder pain syndrome (IC/BPS) is linked to bladder and/or pelvic pain, pressure, and discomfort with urinary frequency. Despite guidelines, there is a need for better treatment options. This study analyzed patient demographics, clinical characteristics, and treatment patterns for medications and procedures in ...
Jaromir Mikl   +8 more
wiley   +1 more source

Downstream Treatment Burden and Health‐Care Utilization Following Initiation of GLP‐1 Receptor Agonists or SGLT2 Inhibitors in Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5163-5173, June 2026.
ABSTRACT Aims Glucagon‐like peptide‐1 (GLP‐1) receptor agonists and sodium–glucose cotransporter 2 (SGLT2) inhibitors are widely used for the treatment of type 2 diabetes, yet their downstream consequences in routine clinical practice remain incompletely characterized.
Yazan Alhamdan   +2 more
wiley   +1 more source

Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]

open access: yes, 2012
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz   +60 more
core   +2 more sources

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

open access: yesAdvanced Science, Volume 13, Issue 27, 13 May 2026.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma   +16 more
wiley   +1 more source

Co-morbidities of Interstitial Cystitis

open access: yesFrontiers in Neuroscience, 2012
Introduction: This study aimed to estimate the proportion of patients with Interstitial Cystitis/Painful Bladder Syndrome (IC/BPS) with systemic dysfunction associated co-morbidities such as irritable bowel syndrome (IBS) and fibromyalgia (FM). Material
Gisela eChelimsky   +5 more
doaj   +1 more source

Mechanotransduction in the Brain: Soliton Theory, Piezo Receptors and MR Elastography in Headache Pathophysiology

open access: yesBrain and Behavior, Volume 16, Issue 5, May 2026.
ABSTRACT Purpose This narrative review aims to explore how incorporating mechanical and thermal dimensions can complement and extend the classical Hodgkin‐Huxley (HH) model to enrich the understanding of headache and pain pathophysiology. Method This review examines the integration of three distinct concepts with the HH model.
Joan Crespi   +5 more
wiley   +1 more source

The efficacy and Safety of Intravesical Bacillus-Calmette-Guerin in the Treatment of Female Patients with Interstitial Cystitis: A double-blinded Prospective Placebo Controlled Study

open access: yesUrology Journal, 2004
Purpose: To evaluate the efficacy and safety of intravesical Bacillus Calmette-Gurein injection in the treatment of female patients with interstitial cystitis.
AA Khezri, M Heidari, Darioush Irani
doaj  

Intravesical hyaluronic acid treatment for ketamine-associated cystitis: Preliminary results

open access: yesUrological Science, 2015
Introduction: Long-term ketamine abuse may cause variable lower urinary tract symptoms (LUTS) and severe cystitis. The clinical features of ketamine-associated cystitis (KC) are very similar to bladder pain syndrome/interstitial cystitis (BPS/IC ...
En Meng   +7 more
doaj   +1 more source

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