Results 1 to 10 of about 781,293 (260)

Nintedanib for systemic sclerosis–associated interstitial lung disease [PDF]

New England Journal of Medicine, 2019
BackgroundInterstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...
Alves, Margarida, Azuma, Arata, Clerisme-Beaty, Emmanuelle, Distler, Oliver, Fischer, Aryeh, Gahlemann, Martina, Girard, Mannaig, Highland, Kristin B., Kuwana, Masataka, Maher, Toby M., Mayes, Maureen D., Raghu, Ganesh, Sauter, Wiebke, SENSCIS Trial Investigator, for the, Smith, Vanessa, Stowasser, Susanne, Tetzlaff, Kay   +16 more
core   +4 more sources

Comparative survival analysis between idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis

Pulmonology, 2020
Introduction Chronic hypersensitivity pneumonitis (CHP) is an interstitial lung disease with limited treatment response and bad prognosis. Sometimes it is indistinguishable from idiopathic pulmonary fibrosis (IPF) becoming one of the main differential ...
Maria Laura Alberti, Jose María Malet Ruiz, Martin Eduardo Fernández, Leandro Fassola, Fabián Caro, Ivette Buendía Roldán, Francisco Paulin   +6 more
doaj   +3 more sources

Inhaled Treprostinil in Pulmonary Hypertension Due to Interstitial Lung Disease.

New England Journal of Medicine, 2021
BACKGROUND No therapies are currently approved for the treatment of pulmonary hypertension in patients with interstitial lung disease. The safety and efficacy of inhaled treprostinil for patients with this condition are unclear.
A. Waxman, R. Restrepo-Jaramillo, T. Thenappan, A. Ravichandran, P. Engel, A. Bajwa, R. Allen, J. Feldman, Rahul G Argula, Peter Smith, K. Rollins, C. Deng, L. Peterson, H. Bell, V. Tapson, S. Nathan   +15 more
semanticscholar   +1 more source

Prevalence, imaging patterns and risk factors of interstitial lung disease in connective tissue disease: a systematic review and meta-analysis

European Respiratory Review, 2023
Introduction Interstitial lung disease (ILD) is a frequent manifestation of connective tissue disease (CTD) with substantial variability in prevalence and outcomes reported across CTD subtypes.
G. Joy, O. A. Arbiv, Carmen K Wong, S. Lok, N. Adderley, K. Dobosz, K. Johannson, C. Ryerson   +7 more
semanticscholar   +1 more source

Long-term nitrofurantoin: an analysis of complication awareness, monitoring, and pulmonary injury cases

BJGP Open, 2021
Background: Long-term nitrofurantoin (NF) treatment can result in pulmonary and hepatic injury. Current guidelines do not outline the type or frequency of monitoring required for detection of these injuries.
Toby Peter Speirs, Nicole Tuffin, Finlay Mundy-Baird, Helena Sakota, Sarah Mulholland, Michelle Westlake, Max Lyon, Andrew R Medford, Charles Sharp, Michael Darby, Mahableshwar Albur, Francis Keeley, Helena Burden, Charlie Kenward, Elizabeth Jonas, Shaney Barratt, Huzaifa I Adamali   +16 more
doaj   +1 more source

Persistent Post–COVID-19 Interstitial Lung Disease. An Observational Study of Corticosteroid Treatment

Annals of the American Thoracic Society, 2021
Rationale: The natural history of recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains unknown. Because fibrosis with persistent physiological deficit is a previously described feature of patients recovering from similar ...
K. Myall, B. Mukherjee, A. M. Castanheira, J. Lam, G. Benedetti, S. Mak, R. Preston, M. Thillai, A. Dewar, P. Molyneaux, A. West   +10 more
semanticscholar   +1 more source

Understanding Interstitial Lung Diseases Associated with Connective Tissue Disease (CTD-ILD): Genetics, Cellular Pathophysiology, and Biologic Drivers

International Journal of Molecular Sciences, 2023
Connective tissue disease-associated interstitial lung disease (CTD-ILD) is a collection of systemic autoimmune disorders resulting in lung interstitial abnormalities or lung fibrosis.
Giuliana Cerro Chiang, T. Parimon
semanticscholar   +1 more source

A multidisciplinary approach to the diagnosis of antisynthetase syndrome

Frontiers in Medicine, 2022
Antisynthetase syndrome is a subtype of idiopathic inflammatory myopathy, strongly associated with the presence of interstitial lung disease. Diagnosis is made by identifying myositis-specific antibodies directed against aminoacyl tRNA synthetase, and ...
Matthew Wells, Sughra Alawi, Kyaing Yi Mon Thin, Harsha Gunawardena, Harsha Gunawardena, Adrian R. Brown, Anthony Edey, John D. Pauling, John D. Pauling, Shaney L. Barratt, Huzaifa I. Adamali   +10 more
doaj   +1 more source

Prevalence and characteristics of progressive fibrosing interstitial lung disease in a prospective registry

European Respiratory Journal, 2022
Background Progressive fibrosing interstitial lung disease (PF-ILD) is characterised by progressive physiological, symptomatic and/or radiographic worsening. The real-world prevalence and characteristics of PF-ILD remain uncertain.
N. Hambly, M. Farooqi, A. Dvorkin-Gheva, K. Donohoe, K. Garlick, C. Scallan, Sy Giin Chong, S. MacIsaac, D. Assayag, K. Johannson, C. Fell, V. Marcoux, H. Manganas, J. Morisset, A. Comes, J. Fisher, S. Shapera, A. Gershon, Teresa To, A. Wong, M. Sadatsafavi, P. G. Wilcox, A. Halayko, N. Khalil, Gerard Cox, L. Richeldi, C. Ryerson, M. Kolb   +27 more
semanticscholar   +1 more source

Differentiating interstitial lung diseases from other respiratory diseases using electronic nose technology

Respiratory Research, 2023
Introduction Interstitial lung disease (ILD) may be difficult to distinguish from other respiratory diseases due to overlapping clinical presentation. Recognition of ILD is often late, causing delay which has been associated with worse clinical outcome ...
Iris G. van der Sar, Marlies S. Wijsenbeek, Gert-Jan Braunstahl, Jason O. Loekabino, Anne-Marie C. Dingemans, Johannes C. C. M. In ‘t Veen, Catharina C. Moor   +6 more
doaj   +1 more source