Results 11 to 20 of about 734,704 (283)

Fibrotic idiopathic interstitial lung disease: the molecular and cellular key players. [PDF]

International Journal of Molecular Sciences, 2021
Interstitial lung disease (ILDs) that are known as diffuse parenchymal lung diseases (DPLDs) lead to the damage of alveolar epithelium and lung parenchyma culminating into inflammation and widespread fibrosis.
Andrisani, D, Beghe', B, Bruzzi, G, Castaniere, I, Cerri, S, Clini, E., Dominici, M, Gozzi, F, Manicardi, L, Marchioni, A, Moretti, A, Samarelli, A, Tabb\uec, L, Tonelli, R   +13 more
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Tocilizumab Prevents Progression of Early Systemic Sclerosis Associated Interstitial Lung Disease [PDF]

Arthritis & Rheumatology, 2021
OBJECTIVE: Tocilizumab has demonstrated lung function preservation in two randomized controlled trials in early systemic sclerosis (SSc). This effect has yet to be characterized in terms of quantitative radiographic lung involvement.
Denton, CP, focuSSced investigators, Furst, DE, Goldin, J, Huang, S, Khanna, D, Kim, GH, Lin, CJF, Roofeh, D   +8 more
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Pathogenesis of systemic sclerosis associated interstitial lung disease [PDF]

Journal of Scleroderma and Related Disorders, 2020
Systemic sclerosis is an autoimmune disease leading to vasculopathy and fibrosis of skin and internal organs. Despite likely shared pathogenic mechanisms, the patterns of skin and lung fibrosis differ.
Denton, CP, Nihtyanova, SI
core   +2 more sources

Comparative survival analysis between idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis

Pulmonology, 2020
Introduction Chronic hypersensitivity pneumonitis (CHP) is an interstitial lung disease with limited treatment response and bad prognosis. Sometimes it is indistinguishable from idiopathic pulmonary fibrosis (IPF) becoming one of the main differential ...
Maria Laura Alberti, Jose María Malet Ruiz, Martin Eduardo Fernández, Leandro Fassola, Fabián Caro, Ivette Buendía Roldán, Francisco Paulin   +6 more
doaj   +3 more sources

Inhaled Treprostinil in Pulmonary Hypertension Due to Interstitial Lung Disease.

New England Journal of Medicine, 2021
BACKGROUND No therapies are currently approved for the treatment of pulmonary hypertension in patients with interstitial lung disease. The safety and efficacy of inhaled treprostinil for patients with this condition are unclear.
A. Waxman, R. Restrepo-Jaramillo, T. Thenappan, A. Ravichandran, P. Engel, A. Bajwa, R. Allen, J. Feldman, Rahul G Argula, Peter Smith, K. Rollins, C. Deng, L. Peterson, H. Bell, V. Tapson, S. Nathan   +15 more
semanticscholar   +1 more source

Diagnosis and monitoring of systemic sclerosis-associated interstitial lung disease using high-resolution computed tomography [PDF]

, 2022
Patients with systemic sclerosis are at high risk of developing systemic sclerosis-associated interstitial lung disease. Symptoms and outcomes of systemic sclerosis-associated interstitial lung disease range from subclinical lung involvement to ...
Brown, Kevin K, Chung, Lorinda, Cottin, Vincent, Distler, Oliver, Goldin, Jonathan G, Kazerooni, Ella A, Khanna, Dinesh, Maher, Toby M, Matteson, Eric L, McNitt-Gray, Michael, Walsh, Simon Lf   +10 more
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Persistent Post–COVID-19 Interstitial Lung Disease. An Observational Study of Corticosteroid Treatment

Annals of the American Thoracic Society, 2021
Rationale: The natural history of recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains unknown. Because fibrosis with persistent physiological deficit is a previously described feature of patients recovering from similar ...
K. Myall, B. Mukherjee, A. M. Castanheira, J. Lam, G. Benedetti, S. Mak, R. Preston, M. Thillai, A. Dewar, P. Molyneaux, A. West   +10 more
semanticscholar   +1 more source

Rheumatoid arthritis-interstitial lung disease: manifestations and current concepts in pathogenesis and management

European Respiratory Review, 2021
Rheumatoid arthritis (RA) is a systemic inflammatory disorder, with the most common extra-articular manifestation of RA being lung involvement. While essentially any of the lung compartments can be affected and manifest as interstitial lung disease (ILD),
S. Kadura, G. Raghu
semanticscholar   +1 more source

Long-term nitrofurantoin: an analysis of complication awareness, monitoring, and pulmonary injury cases

BJGP Open, 2021
Background: Long-term nitrofurantoin (NF) treatment can result in pulmonary and hepatic injury. Current guidelines do not outline the type or frequency of monitoring required for detection of these injuries.
Toby Peter Speirs, Nicole Tuffin, Finlay Mundy-Baird, Helena Sakota, Sarah Mulholland, Michelle Westlake, Max Lyon, Andrew R Medford, Charles Sharp, Michael Darby, Mahableshwar Albur, Francis Keeley, Helena Burden, Charlie Kenward, Elizabeth Jonas, Shaney Barratt, Huzaifa I Adamali   +16 more
doaj   +1 more source

Nintedanib in Patients With Autoimmune Disease–Related Progressive Fibrosing Interstitial Lung Diseases: Subgroup Analysis of the INBUILD Trial

Arthritis & Rheumatology, 2022
To analyze the efficacy and safety of nintedanib in patients with fibrosing autoimmune disease–related interstitial lung diseases (ILDs) with a progressive phenotype.
E. Matteson, C. Kelly, J. Distler, A. Hoffmann-Vold, J. Seibold, S. Mittoo, P. Dellaripa, M. Aringer, J. Pope, O. Distler, A. James, R. Schlenker‐Herceg, S. Stowasser, M. Quaresma, K. Flaherty   +14 more
semanticscholar   +1 more source