Results 201 to 210 of about 228,341 (358)

Autoantibody Seropositivity and Risk for Interstitial Lung Disease in a Prospective Male-Predominant Rheumatoid Arthritis Cohort of U.S. Veterans

, 2020
Jake G. Natalini, Joshua F. Baker, Namrata Singh, Tina Mahajan, Punyasha Roul, Geoffrey M. Thiele, Brian C. Sauer, Cheilonda Johnson, Steven M. Kawut, Ted R. Mikuls, Bryant R. England   +10 more
openalex   +2 more sources

SAT0274 THE EFFECT OF RITUXIMAB ON LUNG FUNCTION AND SKIN SCORE IN SYSTEMIC SCLEROSIS-ASSOCIATED INTERSTITIAL LUNG DISEASE. LONG-TERM OBSERVATION [PDF]

, 2019
L. Garzanova, L. P. Ananyeva, O. Koneva, O. Desinova, O. Ovsyannikova, M. Starovoytova, А. В. Волков, С. И. Глухова   +7 more
openalex   +1 more source

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

Insight into the pathogenesis of interstitial lung diseases and near-to-native lung fibrosis models. [PDF]

Eur J Med Res
Štefániková M, Sedláková V, Portakal T, Hampl A, Vaňhara P, Doubková M.   +5 more
europepmc   +1 more source

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

Arthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H.W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Progressive fibrotic interstitial lung diseases in India: national challenges and implications for global health policies. [PDF]

Health Res Policy Syst
Sasikumar S, Patidar S.
europepmc   +1 more source

A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Treatable Traits in Pediatric Interstitial Lung Diseases: Bridging the Gap to Tailored Therapeutics. [PDF]

J Clin Med
Parisi GF, Papale M, Pecora G, Presti S, Tosto M, Leonardi S.   +5 more
europepmc   +1 more source

Online multidisciplinary discussion on interstitial lung disease: Using new technologies to connect general hospitals to expert units.

Joel Francesqui, Mariana Benegas, Elena Laserna, Leticia Valera, Sandra Cuerpo, Fernanda Hernández‐González, Mario Serrano, Marcelo Sánchez, Jacobo Sellarés   +8 more
openalex   +2 more sources

Late‐onset noninfectious interstitial lung disease following autologous haematopoietic stem cell transplantation in paediatric patients [PDF]

, 2016
Y.-B. Lee, Rimm Huh, Jihyun Kim, Kangmo Ahn, Ki Woong Sung, Joongbum Cho   +5 more
openalex   +1 more source