Results 211 to 220 of about 228,341 (358)

Long‐Term Outcomes of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Systemic Sclerosis Patients with Impaired Cardiac Function

open access: yesArthritis &Rheumatology, Accepted Article.
Objective High intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced SSc. The role of reduced intensity conditioning (RIC) prior to AHSCT in this population remains unclear. We conducted this study to determine the long‐term outcomes of RIC AHSCT in SSc patients with cardiac ...
Yonatan Lean   +4 more
wiley   +1 more source

Exposure-Efficacy Meta-Model of Nintedanib in Adult Patients With Chronic Fibrosing Interstitial Lung Diseases. [PDF]

open access: yesCPT Pharmacometrics Syst Pharmacol
Hartmann S   +4 more
europepmc   +1 more source

Impact of evolving treatment patterns on interstitial lung disease progression in systemic sclerosis using the EUSTAR database

open access: yesArthritis &Rheumatology, Accepted Article.
Background The treatment landscape for systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) has evolved with increasing immunosuppressive (IST) and anti‐fibrotic therapies available. However, their real‐world use remains unclear. Objectives To analyze treatment trends and the effect of IST and anti‐fibrotic therapies on ILD progression ...
Corrado Campochiaro   +17 more
wiley   +1 more source

Neurocognitive Dysfunction in Fibrosing Interstitial Lung Diseases: A Multidimensional Analysis of Pulmonary, Cognitive, and Clinical Correlates. [PDF]

open access: yesDiagnostics (Basel)
Vastag Z   +7 more
europepmc   +1 more source

Dynamic Immune Cell Composition, Phenotypes, and Signaling in an Engineered Metastatic Niche

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT In breast cancer patients, metastasis is the stage of disease where prognosis significantly worsens. However, the timing at which metastasis initiates and the location of metastatic lesions in an organ are stochastic, limiting the timely identification of disease and the administration of treatments.
Rebecca S. Pereles   +6 more
wiley   +1 more source

A novel, non-spirometric "BMP index" for predicting severe adverse outcomes in fibrosing interstitial lung diseases. [PDF]

open access: yesSci Rep
Huang TH   +14 more
europepmc   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

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