Results 61 to 70 of about 3,546,741 (346)

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

A linear time algorithm to compute square of interval graphs and their colouring

AKCE International Journal of Graphs and Combinatorics, 2016
The square of a graph G=(V,E), denoted by G2, is a graph on the same vertex set V(G) such that two vertices x and y are adjacent in G2 if and only if there is a path of length one or two between x and y in G.
Satyabrata Paul, Madhumangal Pal, Anita Pal   +2 more
doaj   +1 more source

Coloring problem of signed interval graphs [PDF]

Transactions on Combinatorics, 2019
A signed graph $(G,\sigma)$ is a graph‎ ‎together with an assignment of signs $\{+,-\}$ to its edges where‎ ‎$\sigma$ is the subset of its negative edges‎.
Farzaneh Ramezani
doaj   +1 more source

Graph isomorphism completeness for trapezoid graphs

, 2015
The complexity of the graph isomorphism problem for trapezoid graphs has been open over a decade. This paper shows that the problem is GI-complete. More precisely, we show that the graph isomorphism problem is GI-complete for comparability graphs of ...
Takaoka, Asahi
core   +1 more source

Interval matroids and graphs

Discrete Mathematics, 1979
AbstractA base of the cycle space of a binary matroid M on E is said to be convex if its elements can be totally ordered in such a way that for every e ε E the set of elements of the base containing e is an interval. We show that a binary matroid is cographic iff it has a convex base of cycles; equivalently, graphic matroids can be represented as ...
openaire   +3 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

On some Graphs with a Unique Perfect Matching

, 2017
We show that deciding whether a given graph $G$ of size $m$ has a unique perfect matching as well as finding that matching, if it exists, can be done in time $O(m)$ if $G$ is either a cograph, or a split graph, or an interval graph, or claw-free ...
Chaplick, S., Fürst, M., Maffray, F., Rautenbach, D.   +3 more
core   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Dombi Interval Valued Neutrosophic Graph and its Role in Traffic Control Management [PDF]

Neutrosophic Sets and Systems, 2019
An advantage of dealing indeterminacy is possible only with Neutrosophic Sets. Graph theory plays a vital role in the field of networking. If uncertainty exist in the set of vertices and edge then that can be dealt by fuzzy graphs in any application and ...
D. Nagarajan, M.Lathamaheswari, S. Broumi, J. Kavikumar   +3 more
doaj   +1 more source