Results 81 to 90 of about 3,522,534 (301)

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Interval-valued fuzzy threshold graph

open access: yes, 2016
Interval-valued fuzzy threshold graph is an extension of fuzzy threshold graph. In this paper, interval-valued fuzzy threshold graph, interval-valued fuzzy alternating 4-cycle, and interval-valued fuzzy threshold dimension are defined, and certain ...
Tarasankar Pramanik   +2 more
semanticscholar   +1 more source

On counting interval lengths of interval graphs

open access: yesDiscrete Applied Mathematics, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Márcia R. Cerioli   +2 more
openaire   +2 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

- and -labeling problems on interval graphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2017
For a given graph , the - and -labeling problems assign the labels to the vertices of . Let be the set of non-negative integers. An - and -labeling of a graph is a function such that , for respectively, where represents the distance (minimum number of ...
Sk Amanathulla, Madhumangal Pal
doaj   +1 more source

Scale Free Interval Graphs

open access: yesTheoretical Computer Science, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Naoto Miyoshi   +3 more
openaire   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Interval line graphs

open access: yesDiscrete Mathematics, 1984
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

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