Results 81 to 90 of about 3,671,469 (355)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

On the on-line coloring of unit interval graphs with proper interval representation [PDF]

Discrete Mathematics & Theoretical Computer Science
We define the problem as a two-player game between Algorithm and Builder. The game is played in rounds. Each round, Builder presents an interval that is neither contained in nor contains any previously presented interval.
Israel R. Curbelo, Hannah R. Malko
doaj   +1 more source

On interval number in cycle convexity [PDF]

Discrete Mathematics & Theoretical Computer Science, 2018
Recently, Araujo et al. [Manuscript in preparation, 2017] introduced the notion of Cycle Convexity of graphs. In their seminal work, they studied the graph convexity parameter called hull number for this new graph convexity they proposed, and they ...
Julio Araujo, Guillaume Ducoffe, Nicolas Nisse, Karol Suchan   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Simultaneous Interval Graphs [PDF]

, 2010
In a recent paper, we introduced the simultaneous representation problem (defined for any graph class C) and studied the problem for chordal, comparability and permutation graphs. For interval graphs, the problem is defined as follows. Two interval graphs G_1 and G_2, sharing some vertices I (and the corresponding induced edges), are said to be ...
Jampani, Krishnam Raju, Lubiw, Anna
openaire   +2 more sources

Incidence matrices and interval graphs [PDF]

Pacific Journal of Mathematics, 1965
Abstract : According to present genetic theory, the fine structure of genes consists of linearly ordered elements. A mutant gene is obtained by alteration of some connected portion of this structure. By examining data obtained from suitable experiments, it can be determined whether or not the blemished portions of two mutant genes intersect or not, and
Fulkerson, D. R., Gross, O. A.
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The niche graphs of interval orders

Discussiones Mathematicae Graph Theory, 2014
The niche graph of a digraph D is the (simple undirected) graph which has the same vertex set as D and has an edge between two distinct vertices x and y if and only if N+D(x) ∩ N+D(y) ≠ ∅ or N−D(x) ∩ N−D(y) ≠ ∅, where N+D(x) (resp.
Park Jeongmi, Sano Yoshio
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

The order difference interval graph of a group [PDF]

Transactions on Combinatorics, 2012
In this paper we introduce the concept of order difference interval graph ¡ODI (G) of a group G. It is a graph ¡ODI (G) with V (¡ODI (G)) = G and two vertices a and b are adjacent in ¡ODI (G) if and only if o(b) − o(a) ∈ [o(a), o(b)].
P. Balakrishnan, R. Kala
doaj