Results 101 to 110 of about 202,689 (293)

Robust $H_{\infty}$ Interval Observer for Linear Systems With a Controllable Convergence Rate: A Parametric Method

open access: yesIEEE Access, 2019
In this paper, the design method of a robust interval observer for linear systems with time-varying disturbances is proposed. First, the H∞ gain performance is established by constructing the transfer function from disturbances to error dynamic ...
Long-Wen Liu, Da-Ke Gu
doaj   +1 more source

Distributed source identification for wave equations: an observer-based approach

open access: yes, 2010
In this paper, we consider a wave equation on a bounded interval where the initial conditions are known (are zero) and we are rather interested in identifying an unknown source term $q(x)$ thanks to the measurement output $y$ which is the Neumann ...
Chapouly, Marianne, Mirrahimi, Mazyar
core   +4 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Limitations of the Double-Observer Method for Estimating Population Size: A Case Study on the Southern Greater Glider (Petauroides volans)

open access: yesConservation
Monitoring the size of wildlife populations is crucial for the effective implementation of conservation management strategies, and a variety of methods have been developed for this purpose.
Xander Kremer   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Inter- and intra-observer reliability of the Ergonomic Screening and Prioritization Tool to assess the risk level of work-related musculoskeletal disorders in nurses [PDF]

open access: yesطب کار
Introduction: Musculoskeletal Disorders (MSDs) are among the most common occupational diseases, and ergonomics and occupational health engineering specialists need reliable and valid methods for assessing high-risk activities and the factors contributing
Niloofar Rahgoshay   +4 more
doaj  

Interval observers for PDEs: approximation approach

open access: yesIFAC-PapersOnLine, 2016
The problem of interval state estimation is studied for systems described by parabolic Partial Differential Equations (PDEs). The proposed solution is based on a finite-element approximation of PDE, with posterior design of an interval observer for the obtained ordinary differential equation.
Kharkovskaya, Tatiana   +3 more
openaire   +2 more sources

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