Results 41 to 50 of about 4,503,242 (210)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Effects of moderate intensity interval training and sprint interval training in patients having chronic asthma: a randomized clinical trial

The Rehabilitation Journal
Background: Pulmonary functions are greatly affected in youngsters as asthma has greatly impacted on cardiorespiratory endurance and quality of life of young adults.
Urba Ashfaq , Bushra Sultana , Farwa Abbas , Muhammad Ali Awan Malik   +3 more
doaj   +1 more source

High Intensity High Volume Interval Training Improves Endurance Performance and Induces a Nearly Complete Slow-to-Fast Fiber Transformation on the mRNA Level

Frontiers in Physiology, 2018
We present here a longitudinal study determining the effects of two 3 week-periods of high intensity high volume interval training (HIHVT) (90 intervals of 6 s cycling at 250% maximum power, Pmax/24 s) on a cycle ergometer.
Julian Eigendorf, Marcus May, Jan Friedrich, Stefan Engeli, Norbert Maassen, Norbert Maassen, Gerolf Gros, Joachim D. Meissner   +7 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Effectiveness of an applied high intensity interval training as a specific operative training

, 2019
The psychophysiological response due to stress of soldiers in actual combat operations have been determined by recent researchers, but there is a lack of knowledge about the most effective training methodologies to prepare these population for these new ...
Curiel Regueros, Agustín, Jesús Fernández-Lucas, Agustín Curiel-Regueros, Fernández Lucas, Jesús, Clemente Suárez, Vicente Javier, Clemente-Suárez, Vicente Javier, Vicente Javier Clemente-Suárez, Curiel-Regueros, Agustín   +7 more
core   +1 more source

Small non-coding RNAs are altered by short-term sprint interval training in men [PDF]

, 2018
Small non-coding RNAs (ncRNAs) are emerging as important molecules for normal biological processes and are deregulated in disease. Exercise training is a powerful therapeutic strategy that prevents cardiometabolic disease and improves cardiorespiratory ...
Aron J. Murphy, Denham, Joshua, Joshua Denham, Murphy, Aron J., Scott-Hamilton, John, John Scott-Hamilton, Amanda D. Hagstrom, Gray, Adrian J., Adrian J. Gray, Hagstrom, Amanda D., Murphy, AJ, Hagstrom, AD, Hagstrom, Mandy ; https://orcid.org/, Scott-Hamilton, J, Denham, J, Gray, AJ   +15 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Sprint Interval Training Decreases Circulating MicroRNAs Important for Muscle Development

, 2017
Small non-coding RNAs, such as microRNAs (miRNAs), have emerged as powerful post-transcriptional regulators of gene expression that play important roles in many developmental and biological processes.
Adrian Gray, Denham, Joshua, Joshua Denham, Scott-Hamilton, John, John Scott-Hamilton, Gray, Adrian, Amanda Hagstrom, Hagstrom, Amanda D.   +7 more
core   +1 more source

A training goal-oriented categorization model of high-intensity interval training

Frontiers in Physiology
There are various categorization models of high-intensity interval training (HIIT) in the literature that need to be more consistent in definition, terminology, and concept completeness.
Thomas L. Stöggl, Thomas L. Stöggl, Tilmann Strepp, Hans-Peter Wiesinger, Hans-Peter Wiesinger, Hans-Peter Wiesinger, Nils Haller, Nils Haller   +7 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source