Results 71 to 80 of about 4,712,109 (313)
Jieqin Ju,1 Jiawen Ma,1 Peizhen Xu,1 Liqing Mao,1 Zizhi Weng,1 Qinhong Xu2 1Intervention Center, The First Affiliated Hospital of Ningbo University, Ningbo, 315010, People’s Republic of China; 2Department of Nursing, The First Affiliated Hospital of ...
Ju J, Ma J, Xu P, Mao L, Weng Z, Xu Q
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Background Bone metastases can compromise the integrity of the spinal canal and cause epidural spinal cord compression (ESCC). The Spinal Instability Neoplastic Score (SINS) was developed in order to evaluate spinal instability due to a neoplastic ...
Lukas Bobinski +4 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Summaries of CDTI activities in Special Intervention Zones (SIZ)
15 ...
Special Intervention Zones +1 more
core
Evaluation of Data Telemetry for Future Leadless Cardiac Pacemaker
Multi-node leadless pacemaker system overcomes the main limitations related to lead complications of the conventional cardiac pacemaker and will thus replace them in the near future.
Pritam Bose +5 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Ethical and existential perspectives : on the meaning of early Intervention
Kapitlet bygger på erfarenheter från det projekt om tidig intervention för barn med funktionshinder i Ryssland och Vitryssland som författaren deltog i och som genomfördes 2004-2009.
Alwall, Jonas
core
Background Exposure to trauma and bereavement is common in conflict-affected regions. Previous research suggests considerable heterogeneity in responses to trauma and loss with varying symptom representations.
Carina Heeke +3 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

