Results 91 to 100 of about 9,738 (308)

EUS-guided endoscopic transgastric necrosectomy in patients with infected necrosis in acute pancreatitis

, 2008
BACKGROUND: Infected pancreatic and peripancreatic necrosis in acute pancreatitis is potentially lethal, with mortality rates up to 35%. Therefore, there is growing interest in minimally invasive treatment options, such as (EUS-guided) endoscopic ...
Besselink, Marc G. H., Weusten, Bas L. A. M., Bollen, Thomas L., Schrover, Ilse M., van Ramshorst, Bert, Timmer, Robin   +5 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Endoscopic Ultrasound‐Guided Bile Duct Drainage Enhances Oncological Systemic Therapy Initiation and Capability in Patients With Non‐Resectable Malignant Distal Bile Duct Obstructions Compared to Percutaneous Transhepatic Biliary Drainage

DEN Open
Introduction Endoscopic retrograde cholangiopancreaticography (ERCP) is the gold standard for bile duct drainage in non‐resectable malignant distal bile duct obstruction with jaundice in pancreaticobiliary and duodenal neoplasia.
Thomas Roland Heiduk, Andre Sasse, Volker Ellenrieder, Lukas Hiebel, Richard Friedemann Knoop, Golo Petzold, Ahmad Amanzada   +6 more
doaj   +1 more source

The Diagnostic Accuracy of Linear Endoscopic Ultrasound for Evaluating Symptoms Suggestive of Common Bile Duct Stones

Gastroenterology Research and Practice, 2016
Background. In order to assess the diagnostic accuracy of linear EUS for evaluating clinically suggestive CBD stones in high-risk groups. Methods. 202 patients with clinically suggestive CBD stones in high-risk groups who underwent linear EUS examination
Min Wang, Xu He, Chuan Tian, Jian Li, Feng Min, Hong-yan Li   +5 more
doaj   +1 more source

Accuracy of diagnosing pancreatic ductal adenocarcinoma by EUS-FNA at a single institution.

, 2015
258 Background: Endoscopic ultrasound-directed fine needle aspiration (EUS-FNA) in combination with imaging is currently the standard preoperative diagnostic method for pancreatic ductal adenocarcinoma (PDA).
Douglas G. Adler, Courtney L. Scaife, Erinn Downs-Kelly, Hannah Beal, Jill E. Shea, Sean J. Mulvihill, Benjamin Witt, Matthew A. Firpo   +7 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Endoscopic ultrasound-guided biliary drainage

, 2016
Endoscopic ultrasound-guided biliary drainage (EUS-BD) is emerging as a safe and effective alternative for endoscopic BD. The advantage of multiple access points from stomach and duodenum allows EUS-BD in patients with altered surgical anatomy and ...
Thawee Ratanchuek, Vinay Dhir, Nonthalee Pausawasdi, Anthony Yuen Bun Teoh, Khek Yu Ho, Majid A. Almadi   +5 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source