Results 191 to 200 of about 92,764 (319)

Disassembly of the TRIM56-ATR complex promotes cytoDNA/cGAS/STING axis–dependent intervertebral disc inflammatory degeneration [PDF]

open access: gold
Wei-Feng Zhang   +18 more
openalex   +1 more source

Leptin Regulates Intervertebral Disc Calcification and Ossification by Promoting Glycolysis Through OCN/HIF‐1α Axis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT During intervertebral disc degeneration (IDD), cartilage endplate (CEP) cells undergo calcification and ossification, relying primarily on glycolysis for energy metabolism. Leptin (LEP) initiates the IDD, while its underlying mechanism related to glycolysis remains elusive in CEP cells. To investigate the underlying mechanism of LEP on IDD, an
Haoxi Li   +7 more
wiley   +1 more source

An overview of mechanical microenvironment and mechanotransduction in intervertebral disc degeneration. [PDF]

open access: yesExp Mol Med
Ke W   +10 more
europepmc   +1 more source

The Implementation of Persistent Spinal Pain Syndrome (PSPS): Mechanism‐Based Recommendations

open access: yesPain Practice, Volume 26, Issue 1, January 2026.
ABSTRACT Background In 2021, the term persistent spinal pain syndrome (PSPS) was introduced. PSPS type 2 (PSPS‐T2) replaced the unsatisfactory term failed back surgery syndrome (FBSS). PSPS type 1 (PSPS‐T1) is a clinical picture of signs and symptoms of FBSS but without prior surgery. PSPS applies to any spinal level.
Simon Thomson   +7 more
wiley   +1 more source

Welfare Indicators for Aquaculture Research: Toolboxes for Five Farmed European Fish Species

open access: yesReviews in Aquaculture, Volume 18, Issue 1, January 2026.
ABSTRACT Refining approaches to measuring, monitoring and appraising animal welfare in aquaculture research is key to (i) protecting and optimizing it, (ii) documenting the severity of how and when it deviates, and (iii) ensuring good scientific quality, reliable results and reproducibility, amongst other factors.
Chris Noble   +50 more
wiley   +1 more source

Association Between Sarcopenia and the Long-Term Risk of Intervertebral Disc Degeneration. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
Chen J   +13 more
europepmc   +1 more source

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