Results 181 to 190 of about 43,248 (263)

Uncertainty Quantification of Central Canal Stenosis Deep Learning Classifier From Lumbar Sagittal T2‐Weighted MRI

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Background Accurate assessment of the severity of central canal stenosis (CCS) on lumbar spine MRI is critical for clinical decision‐making. We evaluated deep learning models for automated CCS grading on sagittal T2‐weighted MRI, focusing on uncertainty quantification to improve clinical reliability.
Adriana Brenzikofer   +5 more
wiley   +1 more source

Lifetime Physical Loading and Magnetic Resonance‐Derived Intervertebral Disc Health in Adults With Chronic Low Back Pain: A Cross‐Sectional Study

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Final multiple linear regression model: heat maps showing Bone‐specific Physical Activity Questionnaire score associations with T2 values in five intervertebral disc (IVD) regions with statistically significant covariates controlled for at individual spinal levels.
Claire L. Samanna   +12 more
wiley   +1 more source

Quantitative Disk and Metabolic Bone PET‐MRI for Understanding Disk‐Endplate Crosstalk in Degeneration of the Lumbar Spine

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Objectives The aim of this investigation was to explore the association between disk degeneration, quantified by Pfirrmann grades and T1rho as a marker of hydration, and bone remodeling in the vertebral endplate quantified by Na[18F]F uptake on PET.
Virginie Kreutzinger   +7 more
wiley   +1 more source

DDRGK1 preserves intervertebral disc development through ufmylation. [PDF]

open access: yesCell Mol Life Sci
Lu M   +7 more
europepmc   +1 more source

Application of Statistical Shape Models to Standard Lumbar MRI for Stenosis Treatment Stratification: Severe Versus Normal Stenosis

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Statistical shape models (SSMs) derived from standard 2D lumbar MRIs capture coordinated morphological features that distinguish severe from normal spinal stenosis. Both intervertebral disc and combined models provide strong discriminatory power, comparable to or exceeding traditional anatomical measurements.
Mary H. Foltz   +4 more
wiley   +1 more source

MRI T2 Relaxation Time of the Intervertebral Disc: Repeatability, the Effect of Time of Day, and Unloaded Rest

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
T2 relaxation time is a commonly used MRI measure of intervertebral disc degeneration. This study investigated the repeatability, as well as the effects of time of day and rest on T2 relaxation time. T2 time repeatability was primarily driven by acquisition factors while time of day and rest changes did not exceed within subject variability. Thus, this
Mackenzie N. Conner   +4 more
wiley   +1 more source

Diagnostic Features of Discogenic Low Back Pain: A Narrative Review and Suggested Areas for Future Research and Clinical Practice

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Background Chronic low back pain is a leading cause of global disability, with discogenic low back pain (DLBP), mechanically stimulated pain arising from the intervertebral disc, representing an important but often under‐recognized subtype. DLBP arises from chronic structural and metabolic changes within the intervertebral disc, leading to ...
William Roger Peters   +2 more
wiley   +1 more source

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