Results 221 to 230 of about 93,770 (350)

Reviewer #2 (Public review): Therapeutic effects of PDGF-AB/BB against cellular senescence in human intervertebral disc

open access: gold
Changli Zhang   +6 more
openalex   +1 more source

Effective management of chronic lumbar back pain in five dogs using an erector spinae plane block

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract This retrospective case series evaluates the use of the ultrasound‐guided erector spinae plane block for managing chronic lumbar pain in five dogs unresponsive to conventional systemic analgesia. Each patient received a bilateral erector spinae plane block at either the L2/L3 or L3/L4 level under general anaesthesia. The injectate consisted of
Nathalie Haslinger, Katrin Ertelt
wiley   +1 more source

Synaptic Vesicle Glycoprotein 2A Suppresses Amyloidogenesis Beyond Its Synaptic Role: A Novel Mechanism Disrupting BACE1 Binding and Altering APP Localization

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Synaptic vesicle glycoprotein 2A, the newly identified APP‐binding protein, reduces amyloid‐β plaque deposition in Alzheimer's disease by suppressing the amyloidogenic pathway through inhibition of BACE1‐APP interaction and alteration of APP endosomal‐lysosomal localization.
Xiaoling Wang   +11 more
wiley   +1 more source

Association Between Sarcopenia and the Long-Term Risk of Intervertebral Disc Degeneration. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
Chen J   +13 more
europepmc   +1 more source

Disassembly of the TRIM56-ATR complex promotes cytoDNA/cGAS/STING axis–dependent intervertebral disc inflammatory degeneration [PDF]

open access: gold
Wei-Feng Zhang   +18 more
openalex   +1 more source

The tandem–random transition of cellular patterning: proposed roles of N‐cadherin‐based orientational cell adhesions in the development, maintenance, and degeneration of the nucleus pulposus

open access: yesBiological Reviews, Volume 101, Issue 1, Page 268-278, February 2026.
ABSTRACT Intervertebral disc degeneration (IDD) can contribute to lower back and neck pain. In IDD, the most affected component of the intervertebral disc is the nucleus pulposus (NP). Derived from the notochord, where cells are organized into a tandem configuration, young NP cells cluster in three‐dimensional (3D) networks embedded in a gelatinous ...
Xiangyun Wei, Nam Vo, Gwendolyn A. Sowa
wiley   +1 more source

Hydrogels Targeting Mechanical-biological signaling transitions of interleukin-33 alleviates intervertebral-disc degeneration. [PDF]

open access: yesMater Today Bio
Zheng J   +12 more
europepmc   +1 more source

Alternative Measures of Body Composition and Outcomes Following Heart Transplant

open access: yesClinical Transplantation, Volume 40, Issue 2, February 2026.
ABSTRACT Current guidelines for heart transplant (HT) listing support body mass index (BMI) < 35 kg/m2, though data supporting this recommendation is mixed. It is unclear if other more specific measurements of body composition are better predictors of outcomes post‐HT.
Ana Lanier   +17 more
wiley   +1 more source

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