Results 281 to 290 of about 93,770 (350)

Transcriptomic and Functional Comparison of Cells Isolated From Healthy and Degenerated Ovine Intervertebral Discs

Journal of Cellular and Molecular Medicine, Volume 30, Issue 2, January 2026.
ABSTRACT Intervertebral disc degeneration (IVDD) is a leading cause of chronic low back pain, yet its cellular and molecular mechanisms remain incompletely understood. Sheep represent a valuable in vivo and ex vivo model for IVDD due to their anatomical and biomechanical similarities with humans and the possibility to access disc samples at early ...
Paul Humbert, Lucie Danet, Emmaëlle Carrot, Floriane Etienne, Boris Halgand, Frédéric Blanchard, Claire Vinatier, Jérôme Guicheux, Marion Fusellier, Catherine Le Visage, Romain Guiho   +10 more
wiley   +1 more source

Diagnosis of degenerative myelopathy in a Boston terrier–French bulldog mixed breed

Journal of Small Animal Practice, Volume 67, Issue 1, Page 86-91, January 2026.
Canine degenerative myelopathy (DM) has been associated with mutations in the superoxide dismutase 1 gene (SOD1). Although the SOD1:c.118G>A mutation has been identified in Boston terriers and French bulldogs, no histological‐confirmed degenerative myelopathy has been reported in either breed.
A. M. K. Chan, J. R. Coates, G. C. Johnson, H. N. Snyman, D. W. Silversides   +4 more
wiley   +1 more source

Disc inflammation and intercellular communication in shaping the immune microenvironment of intervertebral disc degeneration. [PDF]

Front Immunol
Wei M, Zhu K.
europepmc   +1 more source

Endplate chondrocyte-derived exosomal miR-128-3p mitigates intervertebral disc degeneration by targeting TRAF6 via the miR-128-3p/TRAF6 axis to suppress pyroptosis

Qiuwei Li, Ruocheng Guo, Zuomeng Wu, Chenhao Zhao, Xuewu Chen, Hong Wang, Cailiang Shen   +6 more
openalex   +1 more source

The Application of Orthopedic Surgical Robot‐Assisted Technology in Various Clinical Scenarios Involving Bone Tumors

Orthopaedic Surgery, Volume 18, Issue 1, Page 53-65, January 2026.
Robot‐assisted surgery facilitates precise path planning and osteotomy plane identification. With the combination of an orthopedic robot and intraoperative ultrasound or the da Vinci robot, it can enhance the precision and safety of bone tumor surgery. Furthermore, it can be integrated with patient‐specific cutting guides to minimize surgical duration.
Hanxiao Yin, Yiwei Fu, Xirenijiang Yikemu, Weihai Liu, Changye Zou, Xianbiao Xie, Zhiqiang Zhao, Puyi Sheng, Jingnan Shen, Junqiang Yin   +9 more
wiley   +1 more source

TLR4 Induces PANoptosis in Annulus Fibrosus Cells by Activating NLRP12 in Intervertebral Disc Degeneration. [PDF]

J Inflamm Res
Zheng F, Cao L, Fu J, Luo M, Yue W, Ma Y, Chen B, Zhai Y, Liu C.   +8 more
europepmc   +1 more source

Heterogeneity in Lumbar Segmental Bone Mineral Density and Age‐Related Evolution of Whole‐Body Bone Mineral Density: Comprehensive Implications for Osteoporosis Risk Assessment

Orthopaedic Surgery, Volume 18, Issue 1, Page 113-125, January 2026.
The BMDs of several body regions are associated with age and sex, with variations in the rate of change, age at first change, and age‐related trends depending on the anatomical site and sex. The BMDs of L1 and L2 are generally significantly lower than those of L3 and L4.
Jia‐Jun Zhang, Xiong‐Yi Wang, Cheng‐Wei Weng, Miao Zheng, You‐Jia Xu   +4 more
wiley   +1 more source

An Ex Vivo Model of Intervertebral Disc Degeneration for Assessing Retention of Injectable Cell-Based Grafts. [PDF]

JOR Spine
Schmid R, Apte J, Schulze E, Sirek A, Schäfer G, Schäper J, Santini F, Negoias S, Barbero A, Martin I, Pelttari K, Schären S, Krupkova O, Mehrkens A.   +13 more
europepmc   +1 more source

Progress of Programmed Cell Death in Steroid‐Induced Osteonecrosis of the Femoral Head

Orthopaedic Surgery, Volume 18, Issue 1, Page 16-30, January 2026.
Steroid‐induced osteonecrosis of the femoral head is a severe osteoarticular condition resulting from glucocorticoid overuse, characterized by femoral head bone structure collapse and cell death, now predominant among nontraumatic femoral head necroses.
Zhi Kong, Chao Han
wiley   +1 more source

Macrophage Subtypes Distinctly Impact Intervertebral Disc Inflammation and Extracellular Matrix Composition. [PDF]

JOR Spine
Lisiewski LE, Campos L, Jacobsen TD, Kim MKM, Chahine NO.   +4 more
europepmc   +1 more source