As a permanent state of cell cycle arrest, cellular senescence has become an important factor in aging and age-related diseases. As a central regulator of physiology and pathology associated with cellular senescence, the senescence associated secretory ...
Yang Liu +3 more
doaj +1 more source
BMP-2 and TGF-β3 do not prevent spontaneous degeneration in rabbit disc explants but induce ossification of the annulus fibrosus [PDF]
Introduction: Different approaches for disc regeneration are currently under investigation. Beside gene therapy and tissue engineering techniques, the application of growth and differentiation factors own promising potential.
Ferguson, Stephen +2 more
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Objective. Polygonatum sibiricum polysaccharide (PSP) has antioxidant activity, immune enhancement, and other biological properties. However, the effect of PSP on intervertebral disc degeneration has not been reported.
Zhaohui Zhai +3 more
doaj +1 more source
Postoperative low dose CT assessment of interbody fusion two years after thoracoscopic scoliosis surgery [PDF]
The relationship between radiologic union and clinical outcomes in thoracoscopic scoliosis surgery is not clear, as apparent non-union of a spinal fusion does not always correspond to a poor clinical result.
Adam, Clayton +4 more
core +1 more source
Degeneration of the intervertebral disc with new approaches for treating low back pain. [PDF]
This review paper discusses the process of disc degeneration and the current understanding of cellular degradation in patients who present with low back pain.
Binch, AL +3 more
core
Laparoscopic Assisted Fusion of the Lumbosacral Spine: A Biomechanical and Histologic Analysis of the Open Versus Laparoscopic Technique in an Animal Model [PDF]
Study Design. An animal model for laparoscopic lumbosacral fusion. Objectives. To compare the biomechanical and histologic results of open to laparoscopic lumbosacral discectomy and fusion in an animal model. Background Data.
Cahn, Nguyen +6 more
core +1 more source
Pediatric intervertebral disc calcification.
Idiopathic calcification of the intervertebral disc is a rare condition in childhood, of unknown etiology. Calcifications are occasionally discovered on routine radiological examination, or on investigation of nonspecific symptoms such as neck pain, torticollis, fever, and radiculopathy.
IKIZCELI, Tuerkan +3 more
openaire +2 more sources
Investigation of deformation behavior of cervical spine segment during the deformation of the intervertebral disc [PDF]
In this paper the stress-strain state of the model cervical spine segment is regarded. The deformation behavior of the intervertebral disc during the deformation of the intervertebral disc is ...
Рикун, Ю. А.
core
New horizons in spine research: Intervertebral disc repair and regeneration. [PDF]
Iatridis, James C +3 more
core +2 more sources
Intervertebral disc anomaly intelligent classification system based on deep learning, IDAICS
BackgroundIntervertebral disc anomalies, such as degeneration and herniation, are common causes of spinal disorders, often leading to chronic pain and disability.
Zhiheng Gao +9 more
doaj +1 more source

