Results 81 to 90 of about 77,646 (205)

Mechanisms and therapeutic strategies for senescence-associated secretory phenotype in the intervertebral disc degeneration microenvironment

open access: yesJournal of Orthopaedic Translation
As a permanent state of cell cycle arrest, cellular senescence has become an important factor in aging and age-related diseases. As a central regulator of physiology and pathology associated with cellular senescence, the senescence associated secretory ...
Yang Liu   +3 more
doaj   +1 more source

BMP-2 and TGF-β3 do not prevent spontaneous degeneration in rabbit disc explants but induce ossification of the annulus fibrosus [PDF]

open access: yes, 2018
Introduction: Different approaches for disc regeneration are currently under investigation. Beside gene therapy and tissue engineering techniques, the application of growth and differentiation factors own promising potential.
Ferguson, Stephen   +2 more
core  

Protective Effect of Polygonatum sibiricum Polysaccharides on Apoptosis, Inflammation, and Oxidative Stress in Nucleus Pulposus Cells of Rats with the Degeneration of the Intervertebral Disc

open access: yesInternational Journal of Polymer Science, 2019
Objective. Polygonatum sibiricum polysaccharide (PSP) has antioxidant activity, immune enhancement, and other biological properties. However, the effect of PSP on intervertebral disc degeneration has not been reported.
Zhaohui Zhai   +3 more
doaj   +1 more source

Postoperative low dose CT assessment of interbody fusion two years after thoracoscopic scoliosis surgery [PDF]

open access: yes, 2011
The relationship between radiologic union and clinical outcomes in thoracoscopic scoliosis surgery is not clear, as apparent non-union of a spinal fusion does not always correspond to a poor clinical result.
Adam, Clayton   +4 more
core   +1 more source

Degeneration of the intervertebral disc with new approaches for treating low back pain. [PDF]

open access: yes, 2015
This review paper discusses the process of disc degeneration and the current understanding of cellular degradation in patients who present with low back pain.
Binch, AL   +3 more
core  

Laparoscopic Assisted Fusion of the Lumbosacral Spine: A Biomechanical and Histologic Analysis of the Open Versus Laparoscopic Technique in an Animal Model [PDF]

open access: yes, 1997
Study Design. An animal model for laparoscopic lumbosacral fusion. Objectives. To compare the biomechanical and histologic results of open to laparoscopic lumbosacral discectomy and fusion in an animal model. Background Data.
Cahn, Nguyen   +6 more
core   +1 more source

Pediatric intervertebral disc calcification.

open access: yesDiagnostic and interventional radiology (Ankara, Turkey), 2008
Idiopathic calcification of the intervertebral disc is a rare condition in childhood, of unknown etiology. Calcifications are occasionally discovered on routine radiological examination, or on investigation of nonspecific symptoms such as neck pain, torticollis, fever, and radiculopathy.
IKIZCELI, Tuerkan   +3 more
openaire   +2 more sources

Investigation of deformation behavior of cervical spine segment during the deformation of the intervertebral disc [PDF]

open access: yes, 2018
In this paper the stress-strain state of the model cervical spine segment is regarded. The deformation behavior of the intervertebral disc during the deformation of the intervertebral disc is ...
Рикун, Ю. А.
core  

Intervertebral disc anomaly intelligent classification system based on deep learning, IDAICS

open access: yesFrontiers in Radiology
BackgroundIntervertebral disc anomalies, such as degeneration and herniation, are common causes of spinal disorders, often leading to chronic pain and disability.
Zhiheng Gao   +9 more
doaj   +1 more source

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