Results 111 to 120 of about 68,127 (346)

Chronic sequelae and owner burdens are common following canine intervertebral disc disease

open access: yesVeterinary Record, EarlyView.
Abstract Background Canine intervertebral disc disease (IVDD) is common and may be managed conservatively or surgically. However, little is known about long‐term sequelae, quality of life and owners’ emotional burden after diagnosis. Methods Information regarding signalment, neuroanatomical lesion localisation, diagnostic imaging results and treatment ...
Frederik Samsøe‐Schmidt   +2 more
wiley   +1 more source

Investigation by the Method of Integral Equations of the Stress State of the Implant an Intervertebral Disk at Axisymmetric Loading

open access: yesМеханика машин, механизмов и материалов, 2013
The stress state of an anisotropic ring disk of an implant of the intervertebral disk at complex axisymmetric loading is investigated in the work. The method of the integral equations is applied to the calculation of a stresses in a disk.
U.V. Karalevich, D.G. Medvedev
doaj  

Self-Supervised Learning for Spinal MRIs [PDF]

open access: yesarXiv, 2017
A significant proportion of patients scanned in a clinical setting have follow-up scans. We show in this work that such longitudinal scans alone can be used as a form of 'free' self-supervision for training a deep network. We demonstrate this self-supervised learning for the case of T2-weighted sagittal lumbar Magnetic Resonance Images (MRIs).
arxiv  

Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats

open access: yesVIEW, EarlyView.
Peyronie's disease (PD) is a common male reproductive system disorder. The exact etiology of PD remains unclear. This study aimed to investigate molecular and cellular changes in PD using single‐cell spatial transcriptomics. Abstract Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with ...
Keyuan Lou   +6 more
wiley   +1 more source

THE INTERVERTEBRAL DISK PROTHESIS INSTALLATION AFTER ABLATION OF A DISK‘S HERNIA AT CERVICAL LEVEL [PDF]

open access: yesСаратовский научно-медицинский журнал, 2008
The purpose ofthe present work was to study the possibility of use the artificial disk «PRODISK» at cervical level after ablation of intervertebraldisk’s hernia.
I.A.Norkin   +2 more
doaj  

Knockdown of asporin affects transforming growth factor-β1-induced matrix synthesis in human intervertebral annulus cells

open access: yesJournal of Orthopaedic Translation, 2016
Background/Objective: Asporin is associated with osteoarthritis and lumbar disk degeneration. Previous studies in chondrocytes showed that asporin can bind to transforming growth factor-β1 (TGF-β1) and downregulate matrix biosynthesis.
Xu Jiang   +6 more
doaj   +1 more source

Holistic Decomposition Convolution for Effective Semantic Segmentation of 3D MR Images [PDF]

open access: yesarXiv, 2018
Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance in many different 2D medical image analysis tasks. In clinical practice, however, a large part of the medical imaging data available is in 3D. This has motivated the development of 3D CNNs for volumetric image segmentation in order to benefit from more spatial context.
arxiv  

Long-term creep behavior of the intervertebral disk: comparison between bioreactor data and numerical results [PDF]

open access: yes, 2014
The loaded disk culture system is an intervertebral disk (IVD)-oriented bioreactor developed by the VU Medical Center (VUmc, Amsterdam, The Netherlands), which has the capacity of maintaining up to 12 IVDs in culture, for approximately 3 weeks after ...
Alves, J. L.   +7 more
core   +2 more sources

Gastric dilatation secondary to incarceration through a gastrosplenic omental rent in a dog

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 2‐year‐old, entire, female Dogue de Bordeaux presented with inappetence and abdominal distension. Radiographs revealed gastric dilatation and malpositioning. Given the absence of classical signs of gastric dilatation and volvulus, a medical approach was elected. After 24 hours, the dog's condition deteriorated.
Clara Galvani   +4 more
wiley   +1 more source

BRD4/MAP2K7/PGF Signaling Axis Promotes Senescence and Extracellular Matrix Metabolism of Nucleus Pulposus Cells in Intervertebral Disk Degeneration

open access: yesAging Cell, EarlyView.
This study identifies BRD4 as a key regulator in intervertebral disk degeneration (IDD), linking its upregulation to NP cell senescence and disrupted ECM metabolism through the BRD4/MAP2K7/PGF signaling cascade, offering a potential therapeutic target for IDD treatment.
Guangzhi Zhang   +6 more
wiley   +1 more source

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