Results 131 to 140 of about 22,569 (256)

Structural Characterization of Cardiac Free‐Running Purkinje Fibers Using Inhomogeneous Magnetization Transfer (ihMT): A Proof of Concept MRI‐Histology Approach

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
The cardiac Purkinje network is essential for synchronized ventricular activation but remains difficult to visualize with conventional MRI due to limited structural contrast. This study demonstrates that inhomogeneous magnetization transfer imaging provides enhanced contrast that differentiates free‐running Purkinje fibers, Purkinje‐Myocardial Junction,
Arash Forodighasemabadi, Evgenios N. Kornaropoulos, Marion Constantin, Lucas Soustelle, Fanny Vaillant, Jude Leury, Richard Walton, Olivier Bernus, Bruno Quesson, Olivier M. Girard, Guillaume Duhamel, Julie Magat   +11 more
wiley   +1 more source

Structural changes of the multifidus in animal models of intervertebral disk degeneration: a systematic review. [PDF]

Front Surg
Wang Y, Zhao X, Zhang X, Yang Y, Zhang W, Liu S, Liu Z, Zhang L, Wang K, Wu H.   +9 more
europepmc   +1 more source

Quantitative ²³ Na-MRI of the intervertebral disk at 3 T. [PDF]

NMR Biomed, 2022
Çavuşoğlu M, Pazahr S, Ciritsis AP, Rossi C.   +3 more
europepmc   +1 more source

Simultaneous Water‐Specific and Fat‐Specific T1 and Fat Fraction Mapping of the Abdomen in Free Breathing Conditions With a Radially Encoded MP2RAGE

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
A radially encoded MP2RAGE with alternated fat and water selective pulses to enable 3D abdominal imaging and quantitative parameter mapping in free breathing conditions and simultaneously provide proton‐density fat fraction, water‐specific and fat‐specific T1 maps.
Nadège Corbin, François Maingault, Aurélien J. Trotier, Emile Kadalie, Laurence Dallet, Marc Biran, Sylvain Miraux, Eric Thiaudière, William Lefrançois, Emeline J. Ribot   +9 more
wiley   +1 more source

Silk fibroin-collagen hydrogel loaded with IGF1-CESCs attenuates intervertebral disk degeneration by accelerating annulus fibrosus healing in rats. [PDF]

Front Pharmacol
Tian Z, Shen Z, Chen H, Zhao P.
europepmc   +1 more source

Potential molecular targets and drugs for basement membranes-related intervertebral disk degeneration through bioinformatics analysis and molecular docking. [PDF]

BMC Musculoskelet Disord, 2023
Zhou Z, Qin W, Zhang P, He J, Cheng Z, Gong Y, Zhu G, Liang, Ren H, Jiang X, Sun Y.   +10 more
europepmc   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, Volume 183, Issue 11, Page 2660-2674, June 2026.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

Chrysin attenuates intervertebral disk degeneration via dual inhibition of matrix metalloproteinases and senescence: integrated network pharmacology, molecular docking, and experimental validation. [PDF]

Front Med (Lausanne)
Pang Z, Hu J, Zhao C, Li X, Zhu Y, Li X, Wang Y, Zhou Q, Li P.   +8 more
europepmc   +1 more source

Hsa_circ_0001946 Ameliorates Mechanical Stress-induced Intervertebral Disk Degeneration Via Targeting miR-432-5p and SOX9. [PDF]

Spine (Phila Pa 1976), 2023
Xiang Q, Wang J, Cheng Z, Zhao K, Gan W, Chen Y, Zhang Y.   +6 more
europepmc   +1 more source

Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease

Immunology, Volume 178, Issue 2, Page 218-230, June 2026.
This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley   +1 more source