Spine Surgery and Related Research, 2022 Introduction: Intervertebral disk degeneration is a universal and natural process. However, no reports have summarized anatomical age-related intervertebral disk height and disk degenerative changes in the thoracolumbar spine or examined sex-specific ...
Masaaki Machino +6 more
doaj +2 more sources
Intervertebral Disk Degeneration: The Microenvironment and Tissue Engineering Strategies
Frontiers in Bioengineering and Biotechnology, 2021 Intervertebral disk degeneration (IVDD) is a leading cause of disability. The degeneration is inevitable, and the mechanisms are complex. Current therapeutic strategies mainly focus on the relief of symptoms, not the intrinsic regeneration of the ...
Yiming Dou +4 more
doaj +2 more sources
Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation [PDF]
Journal of Veterinary Internal Medicine, 2017 Background: Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL-IVDH) in dogs. Hypothesis/Objectives: To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with ...
Aikawa +34 more
core +2 more sources
Clinical and magnetic resonance imaging characteristics of thoracolumbar intervertenral disk extrusions and protrusions in large breed dogs [PDF]
Veterinary Radiology & Ultrasound, 2016 It has recently been shown that the fat-derived hormone adiponectin has the ability to decrease hyperglycemia and to reverse insulin resistance. However, bacterially produced full-length adiponectin is functionally inactive. Here, we show that endogenous
Beltran, E +5 more
core +5 more sources
Frontiers in Veterinary Science, 2018 Muscle signal alteration detected on MRI is seen in diverse pathologic conditions. We observed signal alterations within the paraspinal muscles in dogs with acute thoracolumbar intervertebral disk extrusion.
Peter Trampus +5 more
doaj +2 more sources
Molecular Therapy: Nucleic Acids, 2019 Intervertebral disk (IVD) degeneration is often associated with severity of lower back pain. IVD core is an avascular, highly hydrated tissue composed of type II collagen, glycosaminoglycans, and proteoglycans.
Chin-Yu Lin +5 more
doaj +2 more sources
Evaluation of magnetic resonance imaging guidelines for differentiation between thoracolumbar intervertebral disk extrusions and intervertebral disk protrusions in dogs [PDF]
Veterinary Radiology & Ultrasound, 2016 Four MRI variables have recently been suggested to be independently associated with a diagnosis of thoracolumbar intervertebral disk extrusion or protrusion.
Aikawa +48 more
core +2 more sources
Cytokine Imbalance as a Biomarker of Intervertebral Disk Degeneration. [PDF]
Int J Mol Sci, 2023 The intervertebral disk degeneration (IDD) and its associated conditions are an important problem in modern medicine. The onset of IDD may be in childhood and adolescence in patients with a genetic predisposition.
Shnayder NA +7 more
europepmc +2 more sources
Current status and development direction of immunomodulatory therapy for intervertebral disk degeneration. [PDF]
Front Med (Lausanne), 2023 Gao Y +5 more
europepmc +3 more sources
Overexpression of BNIP3 in rat intervertebral disk cells triggers autophagy and apoptosis [PDF]
Archives of Biological Sciences, 2022 Excessive apoptosis of intervertebral disk cells and intervertebral disk degeneration (IDD) is the prime cause of low back pain. B-cell lymphoma 2 (Bcl-2) and adenovirus E1B 19 kDa interacting protein 3 (BNIP3), a member of the Bcl-2 family, are involved
Tingsheng Wu +5 more
doaj +1 more source