Results 51 to 60 of about 22,569 (256)

OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor

Arthritis &Rheumatology, EarlyView.
Objective To verify the pathogenesis of the opioid growth factor receptor like‐1 (OGFRL1) loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a patient with chronic recurrent multifocal osteomyelitis (CRMO) and to investigate the underlying mechanism.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Cervical Intervertebral Disk to Vertebral Body Ratios of Different Dog Breeds Based on Sagittal Magnetic Resonance Imaging

Frontiers in Veterinary Science, 2018
Objective: To establish sagittal area and length reference values and ratios between apparently normal canine cervical vertebrae and intervertebral disks using magnetic resonance imaging.Sample: Retrospective evaluation of cervical vertebral column ...
Pia Düver, Christina Precht, Geoffrey Fosgate, Franck Forterre, Bianca Hettlich   +4 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

The Impact of Aging on the Anatomical Course of the Azygos Vein: A Retrospective, Computed Tomography Study

Clinical Anatomy, EarlyView.
ABSTRACT The azygos vein (AV) is typically described as ascending vertically to the right of the vertebral column before arching anteriorly to drain into the superior vena cava. However, a small number of studies suggest that it is found leftward in older adults.
Lauren R. Hector, Hania Paverd, Arthikkaa Thavakumar, Cecilia Brassett, Timothy J. Sadler   +4 more
wiley   +1 more source

Cyclin-Dependent Kinase 9 (CDK9) Inhibitor Atuveciclib Suppresses Intervertebral Disk Degeneration via the Inhibition of the NF-κB Signaling Pathway

Frontiers in Cell and Developmental Biology, 2020
Intervertebral disk degeneration (IVDD) is a spinal disk condition caused by an inflammatory response induced by various proinflammatory cytokines, such as interleukin (IL)-1β and tumor necrosis factor (TNF)-α.
Weiyu Ni, Weiyu Ni, Feizhou Zhang, Lin Zheng, Lin Zheng, Lili Wang, Yi Liang, Yi Liang, Yuhong Ding, Yuhong Ding, Jasper H. N. Yik, Dominik R. Haudenschild, Shunwu Fan, Shunwu Fan, Ziang Hu, Ziang Hu   +15 more
doaj   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

The conservative treatment of cervical hernia in dogs: the importance of respecting procedures – A case study [PDF]

Medicamentul Veterinar, 2019
The intervertebral disk herniation is an abnormal disposal of the nucleus pulposus and/or annulus fibrosus. The displacement can be found in the vertebral canal and/or intervertebral foramen.
Anca Bulai, Maria Crivineanu, Diana Mihaela Alexandru   +2 more
doaj  

Análise comparativa histopatológica entre a hérnia de disco contida e extrusa Análisis comparativo histopatológico entre hernia discal contenida y extruida Comparative histopathologic analysis of contained and extruded disc herniation

Coluna/Columna, 2011
OBJETIVO: Nosso estudo tem o objetivo de estudar as alterações histopatológicas, tais como neovascularização, infiltrado inflamatório, celularidade, apoptose, degeneração mucoide, alterações granulares e calcificação presentes nos tipos de hérnia ...
Luciano Miller Reis Rodrigues, Thérèse Theodoro Rachell, Ana Maria Mader, Carlo Milani, Fabrício Hidetoshi Ueno, Maria Aparecida da Silva Pinhal   +5 more
doaj   +1 more source

Factors Affecting Outcomes in Anterior Cervical Spine Surgery

The Laryngoscope, EarlyView.
This retrospective cohort study examined perioperative complications after anterior cervical spine surgery (ACSS) in 3401 patients treated at a tertiary academic institution. Otolaryngologist co‐surgeons in revision and upper cervical spine (C1‐4) cases, and high‐volume spine surgeons (≥ 15 annual cases) were associated with lower complication rates ...
Nana‐Hawwa Abdul‐Rahman, Hansen Deng, Jonathan Goulazian, Cynthia McMahan, Peter C. Gerszten, Carl H. Snyderman   +5 more
wiley   +1 more source

Social Determinants of Spinal Pathology in Adolescents From Urban Centers in the Post‐Medieval Netherlands (1650–1850 CE)

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT The study of trauma in individuals undergoing growth and development remains an understudied area of research but can provide unique insights into the lived experiences and social identities of young people in the past. This study examines vertebral compression fractures and Schmorl's nodes in children and adolescents (1–20 years at death ...
Meghan D. Langlois, Rachel Schats, Sarah Burrow, Megan B. Brickley   +3 more
wiley   +1 more source