Results 81 to 90 of about 20,153 (223)
Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease
This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley +1 more source
Dehnel's Phenomenon in Mammals
Some small mammals, which remain active year‐round, undergo reversible reductions in body size, braincase height, and the mass of internal organs, including the brain, from summer to winter. It is called Dehnel's phenomenon. In this review, we summarise knowledge of the mechanisms, adaptive value, and genetic basis of the phenomenon, and show how new ...
Jan R. E. Taylor +2 more
wiley +1 more source
The epidural spinal abscess is a purulent collection located between the dura mater and the rachimedular duct, being an unusual entity but a devastating situation, and causing a high morbimortality if it is not followed adequately.
Nereida Rosa Estorino Escaig +2 more
doaj
ABSTRACT Objectives Low back pain is a common pathology in the general population. In people over 60 years of age, it is associated with degenerative changes that cause narrowing of the vertebral canal. Its treatment includes conservative measures and even surgery with decompression and fusion.
Juan Carlos Acevedo‐Gonzalez +3 more
wiley +1 more source
Awake Percutaneous Cervical Cordotomy in Patients With Cancer: A Technical Report
ABSTRACT Background Percutaneous cervical cordotomy (PCC) is a minimally invasive radiofrequency procedure for intractable unilateral cancer pain. Commonly performed under conscious sedation, awake PCC enables real‐time patient feedback, potentially improving targeting precision and expanding eligibility for patients in whom sedation poses risks ...
Adinda P. Pradhana +6 more
wiley +1 more source
Rotary‐wing aircrew have reported the occurrence of neck pain, potentially associated with rapid scanning tasks and head‐supported mass (HSM). The aim of this study is to gain additional insight into the interaction of HSM and neck positions with the innervated tissues in the neck.
Prasannaah Hadagali +3 more
wiley +1 more source
Clinical Applications of Electrical Conductivity Imaging Using MRI
ABSTRACT Magnetic resonance imaging (MRI) has emerged as a noninvasive technique for probing the electrical properties of biological tissues: electrical conductivity and relative permittivity. This review focuses on the electrical conductivity and provides a comprehensive overview of applications across both low‐ and high‐frequency regimes.
Stefano Mandija +14 more
wiley +1 more source
Schematic diagram of mRNA‐lipid nanoparticles (mRNA‐LNP) and its functional mechanisms, applications, and challenges in cell engineering. This figure details the structural composition of mRNA‐LNPs and the delivery strategy, highlighting three core challenges.
Lina Li +9 more
wiley +1 more source
A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section
JOR SPINE, Volume 9, Issue 2, June 2026.
Neharika Bhadouria +43 more
wiley +1 more source
Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang +12 more
wiley +1 more source

