Results 51 to 60 of about 4,712,276 (285)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Psychosocial factors in functional articulation disorders revealed through parent interviews [PDF]

open access: yes, 1960
Thesis (Ed.M.)--Boston ...
Wakstein, Dorothy Joyce   +1 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

What happens when interviewers ask repeated questions in forensic interviews with children alleging abuse? [PDF]

open access: yes, 2011
This study was designed to explore 1) the ways in which interviewers refocus alleged victims of abuse on their previous responses and 2) how children responded when they were refocused on their previous responses.
La Rooy, David J., Lamb, Michael E.
core   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

A nod in the wrong direction : Does nonverbal feedback affect eyewitness confidence in interviews? [PDF]

open access: yes, 2013
Eyewitnesses can be influenced by an interviewer's behaviour and report information with inflated confidence as a result. Previous research has shown that positive feedback administered verbally can affect the confidence attributed to testimony, but the ...
Daniel J. Gurney   +7 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

EDITORIAL: Journalism with integrity

open access: yesPacific Journalism Review, 2014
This is the third issue Pacific Journalism Review has published on the theme of investigative journalism in recent years. Our first issue (PJR, 2011) followed the first regional Investigative Journalism conference held at the Pacific Media Centre at ...
Wendy Bacon
doaj   +1 more source

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