Current and evolving approaches for improving the oral permeability of BCS Class III or analogous molecules [PDF]
The Biopharmaceutics Classification System (BCS) classifies pharmaceutical compounds based on their aqueous solubility and intestinal permeability. The BCS Class III compounds are hydrophilic molecules (high aqueous solubility) with low permeability ...
Dave, Vivek S+4 more
core +2 more sources
Enhanced Fog Water Harvesting on Superhydrophobic Steel Meshes
Fog harvesting using mesh designs offers a sustainable solution to water scarcity. This study highlights key considerations for fog harvesting research and develops a methodology for a standardized protocol reflecting fog characteristics and environmental conditions.
Pegah Sartipizadeh+3 more
wiley +1 more source
SLC26A6 (also known as putative anion transporter 1 [PAT1]) is a Cl–/HCO3– exchanger expressed at the luminal membrane of enterocytes where it facilitates intestinal Cl– and fluid absorption.
Onur Cil+4 more
doaj +1 more source
Intestinal Absorption of Fucoidan Extracted from the Brown Seaweed, Cladosiphon okamuranus
The aim of this study was to examine the absorption of fucoidan through the intestinal tract. Fucoidan (0.1, 0.5, 1.0, 1.5 and 2.0 mg/mL) was added to Transwell inserts containing Caco-2 cells. The transport of fucoidan across Caco-2 cells increased in a
T. Nagamine+4 more
semanticscholar +1 more source
The hyperoxaluria frequently observed in patients with ileal dysfunction has been attributed to increased intestinal absorption of dietary oxalate. Studies of intestinal oxalate transport were performed to provide understanding of this augmentation of oxalate absorption.
openaire +3 more sources
A Study on Thermal Expansion and Thermomechanical Behavior of Composite Metal Foams
The coefficient of thermal expansion of steel–steel composite metal foam (S‐S CMF) is shown to be lower than that of bulk stainless steel while its performance under compression demonstrate excellent mechanical stability and strength at all temperatures with gradualsoftening from 400 to 600 °C.
Zubin Chacko+2 more
wiley +1 more source
Intestinal absorption and biological effects of orally administered amorphous silica particles
Although amorphous silica nanoparticles are widely used in the production of food products (e.g., as anticaking agents), there is little information available about their absorption and biological effects after oral exposure.
Tokuyuki Yoshida+14 more
semanticscholar +1 more source
Intestinal absorptive function. [PDF]
The normal gut is adapted to intermittent feeding with complex macromolecular substrates of low sodium content. The high permeability of the upper small intestine to sodium, together with sodium rich saliva and pancreaticobiliary secretions results in large sodium fluxes into the lumen.
openaire +3 more sources
The use of the Ussing chamber system to investigate iron absorption by the duodenum, jejunum and ileum in the mouse : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology at Massey University, Palmerston North, New Zealand [PDF]
Iron deficiency anaemia is found in approximately 30% of the worlds population and is particularly prevalent in developing countries. The majority of these deficiencies are due to insufficient absorption of iron from the diet.
Edmunds, Shelley Jane
core
Mesoporous Silica Microspheres by Super‐Fast Alkaline Etching of Micrometer‐Sized Stöber Particles
Microscale silica particles are prepared along with a modified, scalable Stöber synthesis using the continuous addition of tetraethoxy silane to an ethanolic solution of ammonia with KCl. Etching with hydroxide ions at 95 °C gave porous analogs within minutes. Monodisperse particles are isolable in high yield after precipitation in ethanol.
Adrian Vaghar+2 more
wiley +1 more source