Results 151 to 160 of about 1,544,258 (252)

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Advanced Healthcare Materials, EarlyView.
Systematic investigation of antibody orientation strategies in lateral flow immunoassays reveals that a para‐substituted (aminomethyl)phenylboronic acid mediated probe (P‐6) combined with a biotin‐streptavidin test‐line modification achieves a synergistic 14‐ to 19‐fold sensitivity gain over conventional conjugation. Furthermore, multiplexed detection,
Pin‐Hao Wang, Shunmuga Nathan Shunmuga Nainar, Bing‐Han Zhuang, Shun‐Mao Yang, Hong‐Cheu Lin, Yang‐Hsiang Chan   +5 more
wiley   +1 more source

Intestinal Absorption and Anti-Inflammatory Effects of a Low-Molecular-Weight α-Glucan from <i>Flammulina filiformis</i>. [PDF]

Foods
Li Y, He M, Xu Z, Liu J, Zhao H, Hu Q, Pei F, Yang W, Su A.   +8 more
europepmc   +1 more source

Artificial Intelligence-Based Quantitative Structure-Property Relationship Model for Predicting Human Intestinal Absorption of Compounds with Serotonergic Activity. [PDF]

Mol Pharm, 2023
Czub N, Szlęk J, Pacławski A, Klimończyk K, Puccetti M, Mendyk A.   +5 more
europepmc   +1 more source

Prediction of intestinal drug absorption in humans

, 2007
EN-AUSThe study described in this thesis was designed to investigate the use of Immobilized Artificial Membrane (IAM) chromatography alone, or in combination with physiochemical descriptors, for predicting intestinal drug absorption in humans.Thesis ...
Yen, Tai-Ti (Erica)
core  

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

The In Vivo Effect of Amorphous Drug Nanoprecipitates on the Intestinal Absorption of the PROTACs ARV-110 (Bavdeglutamide) and ARV-471 (Vepdegestrant). [PDF]

Mol Pharm
Niessen J, Koziolek M, Indulkar A, Borchardt T, Sjöblom M, Hedeland M, Lennernäs H, Dahlgren D.   +7 more
europepmc   +1 more source

Organic Synthesis of New Secosteroids from Fucosterol, Its Intestinal Absorption by Caco-2 Cells, and Simulation of the Biological Activities of Vitamin D. [PDF]

Mar Drugs, 2023
Komba S, Hase M, Kotake-Nara E.
europepmc   +1 more source

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

Advanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko, Claudia Olaizola‐Rodrigo, Clara Bayona, Teodora Ranđelović, Rosa Monge, Estela Solanas, Sara Oliván, Ignacio Ochoa   +7 more
wiley   +1 more source

Nanoparticles for Synergistic Delivery of Curcumin and Quercetin Based on Zein and Sodium Caseinate: Preparation, Characterization, and Intestinal Absorption. [PDF]

Foods
Li Y, Shi R, Xu Z, Huang T, Wang S, Sang Y, Neves MA, Yu W, Wang X.   +8 more
europepmc   +1 more source

Lopinavir-menthol co-crystals for enhanced dissolution rate and intestinal absorption. [PDF]

J Drug Deliv Sci Technol, 2022
Fayed ND, Arafa MF, Essa EA, El Maghraby GM.   +3 more
europepmc   +1 more source